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Oana Lab
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A lab that uses microfabrication to manipulate and measure cells and molecules one at a time.
AboutAbout the lab
Manipulating and measuring cells and molecules one by one
Oana Lab uses microfabrication technology to develop techniques for manipulating and measuring individual cells and molecules.
The lab explores methods for applying stimuli to individual cells and biomolecules and measuring their responses, as well as for controlling their functions.
This is expected to yield insights that conventional research methods could not provide, and to contribute to applications in medicine and manufacturing as well as to basic life science.
Key terms
- Microfluidic device
- A small chip with channels as thin as a human hair carved into it. Liquids and cells are flowed through it for manipulation and analysis.
- Chromosome
- A structure in the cell nucleus in which DNA is wound around proteins and folded.
- Giant vesicle
- A cell-sized sac made of a lipid membrane that can enclose substances inside.
ResearchResearch themes
Based on microfabrication technology, the lab develops techniques for manipulating and measuring single cells and single molecules. Using these techniques, it explores applying stimuli to individual cells and biomolecules and measuring their responses, controlling their functions, and using them as engineering components.
*Illustrative imageDevices for examining a single cell
Aiming to elucidate the mechanisms of cell reprogramming and differentiation and to apply them to areas such as genetic diagnosis, the lab develops techniques that use microfluidic devices to extract chromosomes from a cell one at a time for manipulation and analysis.
*Illustrative imageDevices for altering cell functions
The lab develops devices that efficiently introduce substances into cells, using a technique that fuses cells with each other by electricity to transfer cytoplasm, and a technique that fuses cells with giant vesicles encapsulating genes.
MembersFaculty
The members of Oana Lab consist of faculty members, project researchers, doctoral, master's, and undergraduate students, and administrative assistants.As of 2026
- Associate ProfessorHidehiro OanaPublications ↗
VoicesStudent voices
Compiled from answers by students who were in the lab. Ratings and reviews reflect individual students' experiences, not the lab's official views.
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Devices for examining a single cell: “Cell culture (HeLa cells) (261 16) Cell culture (HeLa cells) - metaphase, prophase” Doc. RNDr. Josef Reischig, CSc. / CC BY-SA 3.0 (cropped)
- Devices for altering cell functions: “HeLa cells stained with antibody to actin (green) , vimentin (red) and DNA (blue)” GerryShaw / CC BY-SA 3.0 (cropped)
- Related lab (山川研究室): “Prototype robot parallèle PAR4” FrancoisPierrot34 / CC BY-SA 4.0 (cropped)
- Related lab (佐藤文俊研究室): “CYP4F2 protein structure” Maxim Masiutin / CC0 (cropped)
- Related lab (趙研究室): “Quadrixette” HaSe / CC BY-SA 4.0 (cropped)
- Related lab (大島研究室): “PIV analysis of a stalled flat plate” Willa / CC BY-SA 3.0 (cropped)
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