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Oral Functional Molecular Science Lab
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The lab explores how inflammation in the oral cavity, the periphery, and the brain relates to systemic diseases.

AboutAbout the lab
Exploring how oral, peripheral, and brain inflammation relate to systemic disease
To put into practice the Faculty of Dental Science's philosophy of "contributing to overall health through oral health," the Oral Functional Molecular Science Lab carries out both life science research and dental research.
The lab explores how oral inflammation, peripheral inflammation, and neuroinflammation relate to systemic diseases.
In addition to educating graduate students, the lab is responsible for teaching pharmacology to undergraduate students.
Through their research, the lab's members meet researchers from around the world and share their findings globally.
Key terms
- Antitumor immunity
- The action of the body's immune system against cancer cells.
- Chronic inflammation
- A state in which inflammation continues for a long time.
- Neurodegenerative diseases
- A general term for diseases in which nerve cells are gradually damaged and lost.
ResearchResearch themes
The lab explores how oral inflammation, peripheral inflammation, and neuroinflammation relate to diseases throughout the body. The lab's website introduces the following four themes.
*Illustrative imageAnalysis of Molecules That Enhance Antitumor Immunity
The lab analyzes how new anticancer signaling molecules that activate antitumor immunity work.
*Illustrative imageChronic Inflammation and Abnormal Glucose and Lipid Metabolism
The lab studies abnormal glucose and lipid metabolism caused by chronic inflammation in peripheral tissues.
*Illustrative imageResearch on Dementia and Neurodegenerative Diseases
The lab conducts research on Alzheimer's disease dementia and other neurodegenerative diseases.
*Illustrative imageEffects of Systemic Chronic Inflammation on the Brain
The lab studies how chronic systemic inflammation affects brain function.
MembersFaculty
The members of the Oral Functional Molecular Science Lab are faculty at the ranks of Professor, Associate Professor, and Assistant Professor.
- ProfessorTakashi Kanematsu
- Associate ProfessorWu Zho
- Assistant ProfessorTomomi Sano
- Assistant ProfessorAyano Ogura
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Oral cancer (1) squamous cell carcinoma histopathology” No machine-readable author provided. KGH assumed (based on copyright claims). / CC BY-SA 3.0 (cropped)
- Analysis of Molecules That Enhance Antitumor Immunity: “Tumor microenvironment” Frontiers in Oncology / CC BY 3.0 (cropped)
- Chronic Inflammation and Abnormal Glucose and Lipid Metabolism: “Glucosa - Insulina diabetes” Abraham Zakik / CC BY-SA 4.0 (cropped)
- Research on Dementia and Neurodegenerative Diseases: “Deep Brain Stimulation (DBS) of Nucleus Basalis of Meynert” Zhang Q, Kim Y-C and Narayanan NS / CC BY 4.0 (cropped)
- Effects of Systemic Chronic Inflammation on the Brain: “Mikroglej 1” No machine-readable author provided. GrzegorzWicher~commonswiki assumed (based on copyright claims). / Public domain (cropped)
- Related lab (Oral Preventive Medicine Lab): “Toothbrush x” Jonas Bergsten / Public domain (cropped)
- Related lab (Molecular Oral Anatomy Lab): “Bone degrading cells - Osteoclast precursors 2 -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Related lab (Oral Function Analysis Lab): “1402 The Tongue” OpenStax / CC BY 4.0 (cropped)
- Related lab (Maxillofacial Tumor Control Lab): “Cleft palate alveolus panorex xray” Coronation Dental Specialty Group / CC BY-SA 4.0 (cropped)
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