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Pathophysiological Information Analysis Lab
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This lab studies pathophysiology, investigating the mechanisms of blood disorders, immunity, and cancer.
AboutAbout the lab
Exploring disease mechanisms through genes and immunity
At the Pathophysiological Information Analysis Lab, faculty members of the Medical Laboratory Science Division study blood diseases, autoimmunity, gastric cancer metastasis, and more.
The lab works on applying genetic analysis to the diagnosis of blood diseases, and on developing methods for inducing tumor immunity and related laboratory testing technologies.
It also investigates how the autoimmune regulator gene AIRE protects against Candida infection.
Another study examines the mechanism of gastric cancer metastasis, focusing on proteins in the cell membrane.
Key terms
- Genetic analysis
- Examining the sequences and changes of genes. Its application to the diagnosis of blood diseases is a research theme.
- Tumor immunity
- The mechanism by which the body's immune system acts against tumors. Developing methods for inducing it and related laboratory testing technologies is a research theme.
- Autoimmunity
- A condition in which the immune system reacts to the body's own components. The lab analyzes the function of AIRE, a gene involved in its regulation.
ResearchResearch themes
The Pathophysiological Information Analysis Lab studies the mechanisms of diseases, including blood diseases, tumor immunity, autoimmunity, and gastric cancer metastasis. Its research focuses on genes, immunity, and proteins in the cell membrane.
*Illustrative imageDiagnosing blood diseases and genetic analysis
With blood diseases as the keyword, the lab works on applying genetic analysis to diagnosis.
*Illustrative imageMethods for inducing tumor immunity and laboratory testing technologies
The lab develops methods for inducing tumor immunity and laboratory testing technologies.
*Illustrative imageThe function of AIRE and Candida infection
The lab analyzes the function of the autoimmune regulator gene AIRE. With autoimmunity, infection immunity, and Candida as keywords, it studies how AIRE protects against Candida infection.
*Illustrative imageMechanisms of gastric cancer metastasis
Focusing on membrane proteins whose levels change in a cytokine-dependent manner, the lab studies the mechanism of gastric cancer metastasis. EMT and the epigenome are also keywords.
MembersFaculty
- ProfessorShinichi Mizuno
- ProfessorHitoshi Katsuta
- LecturerHironori Kurisaki
- LecturerYuki Tateishi
- Assistant ProfessorYoko Yasuda
- Assistant ProfessorTomoko Kimura
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Warm Autoimmune Hemolytic Anemia ( )” Ed Uthman from Houston, TX, USA / CC BY 2.0 (cropped)
- Diagnosing blood diseases and genetic analysis: “Hairy cell leukemia smear” Paulo Henrique Orlandi Mourao / CC BY-SA 3.0 (cropped)
- Methods for inducing tumor immunity and laboratory testing technologies: “Healthy Human T Cell” NIAID/NIH / Public domain (cropped)
- The function of AIRE and Candida infection: “Candida albicans” Y tambe / CC BY-SA 3.0 (cropped)
- Mechanisms of gastric cancer metastasis: “Histology of normal fundic mucosa” Carrasco G, Corvalan AH / CC BY 3.0 (cropped)
- Related lab (Pathophysiological Function Analysis Lab): “Numerous serological tests based on immunochromatography in Clinical Microbiology after assaying” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
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- Related lab (Biological Function Analysis Lab): “2026 - Blood test samples” Oleg Yunakov / CC BY-SA 4.0 (cropped)
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