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Neurosurgery Lab
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The lab provides clinical care and conducts research in neurosurgery, including brain tumors and cerebrovascular disease.

AboutAbout the lab
Cutting-edge, holistic patient care
The lab provides clinical care and conducts medical research in brain tumors, cerebrovascular disease, and functional neurosurgery.
Founded in 1966, it is one of the long-established neurosurgery departments in Japan.
For brain tumors, the lab uses intraoperative electrophysiological monitoring and neuronavigation to achieve maximal resection while preserving brain function.
Alongside holistic care, the lab aims to train academic neurosurgeons who will lead the next generation.
Key terms
- Neuronavigation
- A technique used during surgery in which imaging is used to confirm one's position within the brain while proceeding
- Glioblastoma
- One of the highly malignant tumors that arise in the brain (a type of glioma)
- CAR-T cell therapy
- A treatment in which immune cells (T cells) are genetically engineered to recognize cancer, enabling them to attack it
ResearchResearch themes
The lab works to strengthen its research alongside clinical care. Researcher profiles list the treatment of glioblastoma and higher brain function impairment associated with cerebrovascular disease as research themes.
*Illustrative imageCAR-T Cell Therapy for Glioblastoma
The lab studies CAR-T cell therapy for glioblastoma. This is a research theme of Professor Yoshimoto.
*Illustrative imageGlioblastoma Treatment and Mitochondria
As a research theme of Professor Yoshimoto, the lab investigates molecular mechanisms with the aim of establishing mitochondria-targeted treatments for glioblastoma. Research keywords include oncogenes and metabolic abnormalities.
*Illustrative imageHigher Brain Dysfunction in Cerebrovascular Disease
The lab studies impairments of higher brain function and executive function associated with cerebrovascular diseases such as moyamoya disease and internal carotid artery stenosis. This is a research theme of Associate Professor Nakamizo.
MembersFaculty
Members of the Neurosurgery lab consist of faculty (Professors, Associate Professors, Lecturers, Assistant Professors), staff physicians, and graduate students.
- ProfessorKoji Yoshimoto
- Associate ProfessorAkira Nakamizo
- LecturerTaisuke Kuga
- LecturerKoichi Arimura
- Assistant ProfessorNobutaka Mukae
- Assistant ProfessorRyota Kuroki
- Assistant ProfessorRyusuke Hatae
- Assistant ProfessorYuhei Mitsukita
- Assistant ProfessorHiroshi Fujioka
- Assistant ProfessorShunya Tanaka
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Brain Tumor MRI” 作者不詳 / Public domain (cropped)
- CAR-T Cell Therapy for Glioblastoma: “Glioblastoma (1)” No machine-readable author provided. KGH assumed (based on copyright claims). / CC BY-SA 3.0 (cropped)
- Glioblastoma Treatment and Mitochondria: “Brain Tumor on Brain Slice ( )” National Center for Advancing Translational Sciences from Bethesda, MD / Public domain (cropped)
- Higher Brain Dysfunction in Cerebrovascular Disease: “CT Brain Scan” Goleisureintl / CC BY 4.0 (cropped)
- Related lab (Cardiovascular Medicine Lab): “Echocardiogram 4chambers” 作者不詳 / Public domain (cropped)
- Related lab (Neurology Lab): “Functional and anatomical connectivity in the brain using MRI data 05” MGromov / CC BY-SA 4.0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
- Related lab (Pathophysiology and Restorative Internal Medicine Lab): “SEM blood cells” Bruce Wetzel (photographer). Harry Schaefer (photographer) / Public domain (cropped)
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