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Soft Interface Chemistry Lab
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The lab studies the structure and deformation of soft interfaces, such as lipid membranes.

AboutAbout the lab
Exploring the structure and deformation of soft interfaces
The Soft Interface Chemistry Lab studies soft interfaces, such as films of surface-active substances and biological membranes.
Soft interfaces are involved in daily life through foods, cosmetics, and pharmaceuticals, and understanding their function requires clarifying the structure and morphology of the membranes.
The lab combines interfacial tension measurements, microscopy, spectroscopy, and X-ray measurements using synchrotron radiation.
The faculty members belong to the Faculty of Arts and Science and also hold appointments in the Department of Chemistry, Graduate School of Science.
Key terms
- Soft interface
- An interface with soft properties, such as films of surface-active substances and biological membranes
- Lipid vesicle
- A closed, sac-like structure formed by a lipid bilayer. It is used as a model of biological membranes
- Line tension
- The tension acting along the boundary of a domain formed within a membrane
ResearchResearch themes
The lab aims to clarify and control the structure and morphology of soft interface membranes, studying lipid vesicles, which are models of biological membranes, and molecular assemblies. Using “line tension,” “membrane elasticity,” and “molecular miscibility” as keywords, the research proceeds through interfacial tension measurements, microscopy, and X-ray measurements.
*Illustrative imageDomain formation in lipid vesicles
The lab studies how regions (domains) form within lipid vesicles, which are models of biological membranes. It focuses on the property that membranes are not uniform but undergo phase separation.
*Illustrative imageMembrane deformation (budding, pore formation, fusion, and fission)
The lab studies membrane deformation that arises when molecular shape is coupled to membrane curvature. The targets include budding, pore formation, and fusion and fission.
*Illustrative imageStructural transitions of molecular assemblies
By controlling the interactions between molecules, the lab studies the phenomenon in which the structure of a molecular assembly changes into a different structure (structural transition).
*Illustrative imageInteractions between peptides and lipid membranes
The lab studies how amphiphilic peptides interact with lipid bilayers, which correspond to biological membranes.
MembersFaculty
The members of the Soft Interface Chemistry Lab are faculty members, and doctoral, master's, and undergraduate students.As of 2025
- ProfessorTakanori Takiue
- Assistant ProfessorMika Matsuo
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Lipid vesicles with micelles” Kristie.leong / CC BY 3.0 (cropped)
- Domain formation in lipid vesicles: “Phosphatidylcholine liposomes stained with acridine orange” ArkhipovSergey / CC BY-SA 4.0 (cropped)
- Membrane deformation (budding, pore formation, fusion, and fission): “Cell division process” Jerine Victor / CC BY-SA 4.0 (cropped)
- Structural transitions of molecular assemblies: “Liquid Crystal Phase Transition” KarlGaff / CC BY 4.0 (cropped)
- Interactions between peptides and lipid membranes: “Toroidal-, barrel- and carpel AMP model” Patrícia M. Silva, Sónia Gonçalves and Nuno C. Santos / CC BY 3.0 (cropped)
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