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Nano Physical Chemistry Lab
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The lab self-assembles nanoparticles and applies them to biosensors and other uses.
AboutAbout the lab
Creating new materials through nanoparticle self-assembly
The Nano Physical Chemistry Lab creates new functional materials through the self-assembly of nanoparticles and applies them to biosensing.
The lab investigates plasmon resonance, a phenomenon that occurs at the interface between metals and organic substances, across a broad range.
A recent focus is the “plasmonic nanosheet,” a two-dimensional array of silver nanoparticles. The lab is exploring applications of this material, which confines light in a sheet only a few nanometers thick and guides it efficiently.
On the lab’s website, it is introduced as the “Tamada-Okamoto Lab.”
Key terms
- Self-assembly
- A phenomenon in which nanoparticles or molecules gather spontaneously and form an ordered structure
- Plasmonic nanosheet
- A film a few nanometers thick in which silver nanoparticles are arranged in two dimensions. It confines light inside the sheet
- Total internal reflection fluorescence (TIRF) microscope
- A microscope that uses the evanescent light generated under total internal reflection conditions to observe fluorescence only near the substrate interface
ResearchResearch themes
Under the keyword of nanobiotechnology, the lab creates new functional materials through the self-assembly of molecules and nanoparticles, aiming at applications in biosensing. It broadly investigates phenomena of propagating and localized plasmon resonance that occur at metal–organic interfaces.
Plasmonic nanosheets of silver nanoparticles
The lab spreads size-uniform silver nanoparticles at the air–water interface to make “plasmonic nanosheets,” two-dimensional self-assembled films. It examines their optical and electrical properties, aiming at applications in biosensing and bioimaging.
*Illustrative imageBiosensors using nanosheets
The lab is developing new biosensors that use the vivid color change (plasmonic full color) that also occurs with combinations of silver and gold nanoparticles. It succeeded in detecting by the naked eye a very small amount of gold nanoparticles adsorbed onto a stacked silver nanoparticle sheet through an antigen–antibody reaction.
*Illustrative imageHighly sensitive fluorescence bioimaging
The lab used plasmonic nanosheets as the observation substrate of a total internal reflection fluorescence (TIRF) microscope to enhance emission from the interface. It succeeded in fluorescence observation of a narrow interfacial region of 20 nm or less, and uses this to observe the adhesion interface of adherent cells at high resolution.
*Illustrative imageOther research using plasmons
The lab develops high-efficiency LEDs and solar cells using propagating and localized surface plasmon resonance, and conducts the underlying basic research. It also studies the electrical properties of metal nanoparticle sheets and develops composite devices of photofunctional molecules and metal nanoparticles.
MembersFaculty
The members of the Nano Physical Chemistry Lab consist of faculty, master’s and undergraduate students, and technical staff.As of 2026
- ProfessorKaoru Tamada
- Associate ProfessorYusuke Arima
- Assistant ProfessorYuto Kajino
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Příprava nanočástic stříbra” ZuzanaBrabcova / CC BY-SA 4.0 (cropped)
- Biosensors using nanosheets: “Abbott Freestyle Libre 2 glucose sensor-1157” Raimond Spekking / CC BY-SA 4.0 (cropped)
- Highly sensitive fluorescence bioimaging: “Olympus-BX61-fluorescence microscope” Masur / CC BY-SA 3.0 (cropped)
- Other research using plasmons: “Gold and silver nanoparticles in labelled Petri dishes” Drkirstyross / CC BY-SA 4.0 (cropped)
- Related lab (Coordination Chemistry Lab): “U.S. Department of Energy - Science - )” U.S. Department of Energy from United States / Public domain (cropped)
- Related lab (Soft Interface Chemistry Lab): “Lipid vesicles with micelles” Kristie.leong / CC BY 3.0 (cropped)
- Related lab (Dynamic Life Chemistry Lab): “Fluorescence from Fluorescent Proteins” Erin Rod / CC BY-SA 4.0 (cropped)
- Related lab (Photofunctional Materials Chemistry Lab): “Barium ferrite crystal structure” Yilin Evan Li / CC BY-SA 4.0 (cropped)
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