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Malaria Immunology Lab
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A lab that studies the immune response to malaria.
AboutAbout the lab
Exploring how immunity fights malaria
The Malaria Immunology lab studies the immune response to infection with malaria parasites.
Malaria parasites infect both mammals and Anopheles mosquitoes, and have evolved a variety of strategies to evade the host immune system.
Using mouse models of malaria and genetically modified mice lacking various genes, the lab applies imaging and immunological methods to investigate parasite-host interactions and disease pathology.
The lab was established in 2010 at the Immunology Frontier Research Center (IFReC) at Osaka University, and in 2019 it moved its base to the Institute of Medical Science, the University of Tokyo, where it continues its research and education.
Key terms
- Malaria parasite (Plasmodium)
- The parasite that causes malaria. It has a complex life cycle that involves both mammals and Anopheles mosquitoes as hosts
- Innate and adaptive immunity
- The two types of immunity built into the body. Coordination between the two is known to be important against malaria
- Genetically modified mice
- Mice engineered to lack various genes. In this lab, they are used to investigate the pathology of malaria and related questions
NewsLab news
A review article by Assistant Professor Mariana Silva Almeida was published in Current Opinion in Virology
A review article was published in International Immunology
A paper from the lab was published in mBio
A paper on Leishmania was published in Frontiers in Medicine
A paper was selected as a September featured paper in International Immunology
ResearchResearch themes
Coordination between innate and adaptive immunity is known to be important against malaria, and the lab aims to gain a comprehensive understanding of parasite-host interactions and disease pathology. Building on results ranging from basic research to translational research, it aims to develop new strategies, such as therapeutics and vaccines, to protect people from malaria.
View More ↗MembersFaculty
The members of the Malaria Immunology lab consist of faculty, visiting researchers, postdoctoral researchers, and medical students.As of 2026
- ProfessorCevayir Coban
- Assistant ProfessorMariana Silva Almeida
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Malaria falciparum ring forms” Dr Graham Beards / CC BY-SA 4.0 (cropped)
- Related lab (Immunoparasitology Lab): “Toxoplasma parasites (tachyzoites) in a fibroblast host cell” Morne Arin (Ksena Longrin, previously known as Kseniia Bondarenko) / CC BY 4.0 (cropped)
- Related lab (Molecular Immunology Lab): “T Lymphocyte, also known as a T cell (yellow color)” NIAID / CC BY 2.0 (cropped)
- Related lab (Cutaneous Allergy and Host Defense Lab): “Staphylococcus aureus 01” Photo Credit: Janice Carr Content Providers(s): CDC/ Matthew J. Arduino, DRPH; Janice Carr / Public domain (cropped)
- Related lab (Aging Biology Lab): “T Cell Senescence (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
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