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Drug-Resistant Bacteria Lab
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The lab studies the genomes and spread of resistant bacteria that antibiotics cannot kill.

AboutAbout the lab
Uncovering how resistant bacteria spread through their genomes.
As a division of the Japan-Thailand Joint Research Center for Infectious Diseases, the lab studies resistant bacteria that antibiotics cannot kill.
Its central focus is carbapenem-resistant Enterobacteriaceae (CRE), which are resistant to carbapenem antibiotics, regarded as last-resort drugs for intractable infections.
With the cooperation of core hospitals in Thailand and Myanmar, the lab collects clinical isolates of CRE and sequences their genomes.
Using the resulting information, the lab aims to clarify how CRE acquire drug resistance genes and how they spread.
Key terms
- Carbapenem antibiotics
- A class of antibiotics regarded as last-resort drugs for intractable infections.
- CRE
- Bacteria of the family Enterobacteriaceae that are resistant to carbapenem antibiotics. They are also resistant to many other antibiotics, which makes treatment difficult.
- Molecular epidemiology
- A method that uses molecular information such as genomes to trace how resistant bacteria have been transmitted.
ResearchResearch themes
Antibiotics have saved many lives from various infectious diseases, but the emergence of resistant bacteria has become a serious problem in clinical practice. The lab focuses on carbapenem-resistant Enterobacteriaceae (CRE), which are resistant to carbapenem antibiotics.
View More ↗MembersFaculty
The members of the Drug-Resistant Bacteria Lab consist of faculty: a Professor, an Associate Professor, and a Project Associate Professor.
- ProfessorTetsuya Tetsuya
- Associate ProfessorShigeaki Matsuda
- Project Associate ProfessorRyuichiro Abe
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Proteus mirabilis petri” Dr. John J. Farmer / Public domain (cropped)
- Genome analysis of CRE and clarifying their transmission: “Carbapenem-resistant enterobacteriaceae” Bologna, E.; Licari, L.C.; Manfredi, C.; Ditonno, F.; Cirillo, L.; Fusco, G.M.; Abate, M.; Passaro, F.; Di Mauro, E.; Crocetto, F. / CC BY 4.0 (cropped)
- Related lab (Virus Infection Lab): “Aedes aegypti on leaf” Wee Hong / CC BY-SA 4.0 (cropped)
- Related lab (Bacterial Infection Division Lab): “Vibrio cholerae-Darting motility, Gram stain, Culture on solid and liquid media, and Preservation” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Osaka-Mahidol Infectious Diseases Center Lab): “Aedes aegypti biting human” Original author: US Department of Agriculture; then denoised rescaled, enhanced with adaptive denoising filters and minimal resharpening, then unscaled to original resolution, for easier refitting at various resolutions. / Public domain (cropped)
- Related lab (Iwasaki Lab): “Lassa Virus” NIAID / CC BY 2.0 (cropped)
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