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Nakamura Lab
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The lab studies infectious diseases and aims to detect any pathogen using next-generation sequencing technology.
AboutAbout the lab
Finding any pathogen from its genetic information
The Nakamura Lab (Infection Metagenomics Division) studies infectious diseases using next-generation sequencing, structural analysis, and bioinformatics.
The lab was founded with the aim of applying metagenomic analysis, which has been used to search for microorganisms in environmental surveys, to develop a diagnostic method that can detect any pathogen simply and quickly.
In its January 2023 message, the lab states that understanding infectious diseases requires close study of the relationships among infectious microorganisms, commensal microorganisms, and humans.
The lab's English name is Infection Metagenomics, and it is known by the abbreviation iMet.
Key terms
- Next-generation sequencing
- A technology that can read enormous amounts of genetic information. It is used to comprehensively read the genetic information of microorganisms in patient specimens.
- Metagenomic analysis
- A method that has been used in environmental surveys to comprehensively search for microorganisms. The lab aims to apply it to the simple, rapid detection of pathogens.
- Gut microbiota
- The community of bacteria living in the intestine. The lab uses it as a clue for examining changes in humans after disease occurs.
NewsLab news
A Project Technical Staff member of the Japan International Cooperation Agency received the FY2026 (Reiwa 8) Outstanding Engineer Award
A paper by Associate Professor Nakamura and colleagues was published in Clinical microbiology and infection : the official publicat…
A paper by Project Assistant Professor Oki and colleagues was published in The FEBS journal
A paper by Project Assistant Professor Oki and colleagues was published in Nature communications
A paper by Professor Tetsuya and colleagues was published in Biochemical and biophysical research communications
ResearchResearch themes
The lab uses various next-generation sequencing technologies and large-scale computers to research and develop new methods that make it possible to detect all kinds of pathogens. It also investigates how pathogens cause disease in humans and the changes that occur in humans after they become ill.
*Illustrative imageComprehensive pathogen detection methods
The lab studies methods that use next-generation sequencing to comprehensively read the genetic information of pathogenic microorganisms in patient specimens and thereby detect pathogens. It works on increasing the sensitivity of this detection method and on evaluating its comprehensiveness when applied to various infectious diseases.
*Illustrative imageMechanisms of pathogenicity and the gut microbiota
The lab studies the mechanisms of pathogenicity, that is, how pathogens cause disease in humans. It analyzes the changes that occur in humans after disease onset, focusing on the gut microbiota.
MembersFaculty
The members of the Nakamura Lab (Infection Metagenomics Division) consist of faculty, a Visiting Associate Professor, Project Assistant Professors, project researchers, project technical staff, technical assistants, secretaries, doctoral, master's, and undergraduate students, and research students.As of 2026
- ProfessorShota Nakamura
- ProfessorTetsuya Tetsuya
- ProfessorTakayuki Kato
- LecturerDaisuke Motooka
- Project Assistant ProfessorHiroya Oki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “370A automated DNA sequencer” Giac83 / CC BY-SA 2.5 (cropped)
- Comprehensive pathogen detection methods: “DNA-Sequencers from Flickr 57080968” Flickr user jurvetson / CC BY 2.0 (cropped)
- Mechanisms of pathogenicity and the gut microbiota: “Escherichia coli EMB” Gene Drendel / CC BY 4.0 (cropped)
- Related lab (Yamazaki Lab): “RNA pol” 作者不詳 / Public domain (cropped)
- Related lab (Ikawa Lab): “Overview of TALENs” Ogletreerd / CC BY-SA 4.0 (cropped)
- Related lab (Ito Lab): “Potyvirus genome and virion” Jiri Sochor, Petr Babula, Vojtech Adam, Boris Krska, and Rene Kizek / CC BY 3.0 (cropped)
- Related lab (Nakatani Lab): “Medaka (Oryzias latipes) egg, day 0” Ethmostigmus / CC BY-SA 4.0 (cropped)
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