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Kodama Lab
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The lab investigates the pathogenicity of enteric bacterial pathogens and the evolution of epidemic strains.
AboutAbout the lab
Uncovering the mechanisms to move toward infection control that does not rely on antimicrobials.
The Kodama Lab in the Department of Molecular Bacteriology studies the molecular mechanisms by which enteric bacterial pathogens exert pathogenicity.
The lab also works to clarify the evolutionary processes that explain why particular bacterial strains cause global epidemics.
Because of the AMR (antimicrobial resistance) problem, infection control that relies on antimicrobials alone is reaching its limits.
By understanding these mechanisms, the lab aims to create concepts and methods that lead to new infection control strategies that do not depend on antimicrobials.
The department belongs to the Division of Infection Mechanisms at the Research Institute for Microbial Diseases.
Key terms
- AMR (antimicrobial resistance)
- The problem of bacteria becoming less susceptible to antimicrobials, which makes it difficult to control infections with antimicrobials alone.
- Whole-genome analysis
- Analysis that reads and examines the entire set of genetic information a bacterium carries.
- Phylogenetic analysis
- Analysis that compares how closely bacterial strains are related to investigate how they branched and evolved.
ResearchResearch themes
The Kodama Lab works to clarify the molecular mechanisms of pathogenicity expression in enteric bacterial pathogens and the evolutionary processes that drive the emergence and spread of globally epidemic strains. By combining molecular microbiology, infection models, and genomic epidemiology, the lab aims to create new infection control strategies that do not depend on antibiotics.
*Illustrative imageMechanisms of pathogenicity in enteric bacterial pathogens
The lab takes an integrated approach, from identifying virulence factors to analyzing their mechanisms of action and the regulation of gene expression, to study the molecular basis of bacteria-host interactions. It establishes new infection models and experimentally tests how infection is established.
*Illustrative imageEvolutionary mechanisms that give rise to globally epidemic strains
Through international molecular epidemiology studies, the lab investigates why particular bacterial strains cause global epidemics. It identifies genetic factors specific to epidemic strains through whole-genome analysis and phylogenetic analysis of strains from around the world, and tests their functions experimentally.
MembersFaculty
The members of the Kodama Lab are introduced as a Professor and an Associate Professor.As of 2026
- ProfessorToshio Kodama
- Associate ProfessorMasataka Suzuki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “E. coli Bacteria ( )” NIAID / CC BY 2.0 (cropped)
- Mechanisms of pathogenicity in enteric bacterial pathogens: “E coli at 10000x, original” Photo by Eric Erbe, digital colorization by Christopher Pooley, both of USDA, ARS, EMU. / Public domain (cropped)
- Evolutionary mechanisms that give rise to globally epidemic strains: “Phage injecting its genome into bacteria-es” Thomas Splettstoesser. (Traducido al español por Alejandro Porto) / CC BY-SA 3.0 (cropped)
- Related lab (Fujimoto Lab): “Phosphate solubilizing bacteria cultured in petri dish” Joydeep / CC BY-SA 3.0 (cropped)
- Related lab (Watanabe Lab): “Influenza A Virus (H3N )” NIAID / CC BY 2.0 (cropped)
- Related lab (Yamamoto Lab): “T. gondii tachyzoites” Persian Microbiologist / CC BY-SA 4.0 (cropped)
- Related lab (Pathogenic Bacteria Research Group Abe Lab): “Antimicrobial susceptibility testing (AST) result of Leuconostoc” Ajay Kumar Chaurasiya / CC0 (cropped)
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