Labs in The University of Osaka, School of Science

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A lab that measures heat production with an optical microscope and understands it by stimulating it with heat.

The Protein Physical Biology Lab studies phenomena related to heat production in living organisms, aiming to understand them at the spatial scale of the cell. The lab develops methods for local heat stimulation and for measuring temperature with an optical microscope. It applies these methods to experimental systems at various spatial scales, from biomolecules to whole organisms. Together with collaborators in Japan and abroad, the lab pursues both curiosity-driven themes in search of fundamental truths and disease-related themes.

#Thermal biology #Thermogenesis #Temperature measurement

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A lab that designs proteins from scratch on computers.

The Protein Design Lab designs proteins on computers based on physical chemistry and data science, and studies how their structures form and the principles by which their functions emerge. The lab believes that natural proteins are finished products that nature has spent billions of years creating, and that analyzing them alone makes it difficult to clarify the mechanisms by which they work. The lab uses biochemical experiments to examine how the designed proteins actually behave, and uses the results to develop protein design technology. The lab is located in the Advanced Protein Data Science Research Center (ASPiRE), part of the Institute for Protein Research at Osaka University, and the site also introduces it under the name "Koga Lab."

#Protein design #Molecular simulation #Protein engineering

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A lab that seeks to understand how organisms perceive the external world through the structure and function of proteins.

The Biomolecular Recognition Lab aims to understand how organisms perceive the external world, based on the structure and function of protein molecules. The lab's website reports that results of joint research on taste receptors have been published in multiple academic journals. Prof. Yamashita took part in joint research on sweet taste receptors with NARO (National Agriculture and Food Research Organization) and others, contributing from the perspective of receptor structure. The lab opened in December 2024, and Assistant Professor Itoigawa joined in April 2025.

#Taste receptors #Protein structure #External environment perception

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An experimental group that studies atomic nuclei using an accelerator.

The Nuclear Matter Physics Group is a research group that conducts nuclear experiments at the Van de Graaff Experimental Facility on the Toyonaka Campus of Osaka University. At the lab open house, titled “The World of Atomic Nuclei Seen with Accelerators,” it introduces accelerators and experimental equipment. The website advises those considering joining as fourth-year undergraduates or going on to the master's or doctoral program to contact Prof. Fukuda. The content of the website dates from around fiscal 2019.

#Atomic nuclei #Van de Graaff accelerators

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宇宙進化学グループ（長峯研究室） (introduction coming soon)

Astrophysics and cosmology through theory and large-scale numerical simulations: formation and evolution of galaxies and galaxy clusters, general relativistic astrophysics including black holes and gravitational wave emission, gamma-ray bursts, astrophysical jets, cosmic-ray acceleration, and dark matter

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X線天文学グループ（松本研究室） (introduction coming soon)

Observation of high-temperature, high-energy phenomena in the universe, such as hot plasma in galaxy clusters and supernova remnants and the vicinity of black holes, using satellite-borne X-ray CCD cameras and other instruments; development of detectors for future satellites

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理論物質学グループ（波多野研究室） (introduction coming soon)

Treating various phenomena on the surfaces of the Earth and planets as "cooperative phenomena of many-body systems," we study the dynamics and statistical laws of matter and their universality using methods of statistical physics and nonlinear dynamics.

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惑星科学グループ（寺田研究室） (introduction coming soon)

Studies of the early formation history of the solar system and planetary environments through precise isotope ratio measurements and chemical analyses of elements in terrestrial rocks, lunar samples, and meteorites, and magnetic experiments in microgravity

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惑星内部物質学グループ（近藤研究室） (introduction coming soon)

Experimental study of the behavior and phase transitions of materials from the surface to the interior of Earth and planets, based on geophysics and solid-state physics, using high-pressure and high-temperature apparatus combined with various measurement methods

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赤外線天文学グループ（住研究室） (introduction coming soon)

Through infrared observations with ground-based and space telescopes and instrument development, we study exoplanet searches by gravitational microlensing (MOA, PRIME), optical identification of gravitational-wave sources, the structure of the Milky Way, and more.