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Other departments in School of Science ›Faculties at The University of Osaka ›

Hiroyasu Yamaguchi, Professor
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The Supramolecular Functional Chemistry Lab aims to create functional materials that combine the strengths of each component by hybridizing biomacromolecules with synthetic polymers and small molecules. The lab uses monoclonal antibodies in particular as the biomacromolecules. The lab extracts the key points of biomolecular structures and designs and synthesizes molecules and polymers that take over their roles. Recently, the lab has also been working on sulfur-containing polymers made from sulfur, a surplus resource.

Ken Terao, Professor
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The Polymer Solution Science Lab studies the molecular conformation of polymers in solution, the aggregates formed by self-assembly, and the phase separation of solutions. Polymers take an extremely wide variety of forms in solution and show distinctive properties not seen in low-molecular-weight compounds. Using small-angle X-ray scattering, light scattering, and spectroscopy, the lab quantitatively examines structure and properties, from isolated polymer chains to aggregates and nanocomposites. In its recent research highlights, the lab works with derivatives of polysaccharides such as pullulan and amylose, and investigates the structure of micelles formed in aqueous solution, among other topics.

Taro Matsuo, Professor
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The Life and Planetary Evolution Lab conducts research with the aim of understanding the evolution of planets and the evolution of the life they host together, and connecting this to the search for life in space. Targeting planets, moons, and icy bodies in the Solar System as well as exoplanets, the lab uses diverse methods, including computation, telescope observation, development of observation instruments, field surveys on Earth, biology experiments, and planetary exploration. Centered on the perspective of the co-evolution of planets and life, the lab treats Earth as a model for bodies that nurture life. On the lab's website, it is introduced under the name "Life and Planetary Evolution Group."

Masato Nakai, Associate Professor
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The Organelle Biology Lab studies the functions and biosynthesis of proteins that work in chloroplasts and other organelles, the subcellular compartments characteristic of plants and algae. The lab's main theme is how chloroplasts are formed and how they support the life activities of plants. Together with many research groups in Japan and abroad, the lab approaches this question from diverse angles, including plant molecular and cell biology, plant physiology, protein chemistry, and structural biology. On the lab's website, it is also introduced under the name "Nakai Lab."

Takahisa Furukawa, Professor
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The Molecular Developmental Biology Lab studies how the vertebrate central nervous system is built, focusing on the mechanisms of its development. Mainly using the retinal visual system as a model, the lab investigates the path by which genetic programs encoded in the genome generate neurons, shape neural circuits, and lead to the function of nerves in the body. The lab also tackles medical questions of how abnormalities at each level, from genes to physiological function, lead to human disease and how they can be resolved. Graduate students can join through the Graduate School of Science (Department of Biological Sciences), the Graduate School of Frontier Biosciences, or the Graduate School of Medicine.

Akira Shinohara, Professor
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The Genome-Chromosome Function Lab studies the mechanisms that generate the stability and diversity of genes, chromosomes, and DNA. Focusing on homologous recombination, an exchange reaction between DNA molecules, the lab examines the repair of DNA damage and the segregation of chromosomes in meiosis, the cell division that produces eggs and sperm. The lab believes this research will contribute to understanding cancer caused by genome instability, and miscarriage caused by aneuploidy in eggs and sperm. To clarify the molecular mechanisms of recombination and its functions in cells, the lab uses baker's yeast.

Shiroh Iwanaga, Professor
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The Parasitology Lab studies Plasmodium, the malaria parasite that causes malaria, one of the three major infectious diseases, from the standpoint of basic biology. Unlike viruses and bacteria, the malaria parasite is a eukaryote, like us. The lab aims to understand its survival strategy at the molecular level through the mechanisms of gene expression, and to find its weaknesses. Using next-generation sequencer analysis and CRISPR/Cas9, and moving between medicine and basic biology, the lab aims for results that contribute to malaria control. On the lab's website, it is introduced as the "Iwanaga Lab, Division of Molecular Protozoology" of the Research Institute for Microbial Diseases.

Tohru Ishitani, Professor
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The Biological Regulation Lab studies the mechanisms by which the body is formed, maintained, and ages, using imaging and model animals. One pillar of its research is "cell competition," which examines how abnormal cells arising in a cell population are detected by surrounding cells and eliminated. The other pillar is research on predicting and controlling human aging and lifespan using the killifish, an extremely short-lived fish with a lifespan of 3 to 6 months. On the lab's website, it is introduced under the name "Ishitani Lab."

Madoka Suzuki, Independent Associate Professor
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The Protein Physical Biology Lab studies phenomena related to heat production in living organisms, aiming to understand them at the spatial scale of the cell. The lab develops methods for local heat stimulation and for measuring temperature with an optical microscope. It applies these methods to experimental systems at various spatial scales, from biomolecules to whole organisms. Together with collaborators in Japan and abroad, the lab pursues both curiosity-driven themes in search of fundamental truths and disease-related themes.

Nobuyasu Koga, Professor
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The Protein Design Lab designs proteins on computers based on physical chemistry and data science, and studies how their structures form and the principles by which their functions emerge. The lab believes that natural proteins are finished products that nature has spent billions of years creating, and that analyzing them alone makes it difficult to clarify the mechanisms by which they work. The lab uses biochemical experiments to examine how the designed proteins actually behave, and uses the results to develop protein design technology. The lab is located in the Advanced Protein Data Science Research Center (ASPiRE), part of the Institute for Protein Research at Osaka University, and the site also introduces it under the name "Koga Lab."
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