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Oral-Systemic Connection Joint Research Lab
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A joint research lab that explores how bacteria in the mouth relate to systemic diseases.
AboutAbout the lab
Exploring how oral bacteria relate to diseases of the whole body.
The lab studies the correlation between the oral environment and systemic condition, focusing on diseases influenced by periodontopathic and cariogenic bacteria.
It analyzes patients' oral environment and systemic condition on a large scale and over a long period.
Based on the results, it examines the effects of oral bacteria on systemic diseases from both basic and clinical perspectives.
It also aims to spread awareness of how important it is to improve the oral environment in controlling systemic diseases.
Key terms
- Periodontopathic bacteria
- Bacteria that cause periodontal disease
- Cariogenic bacteria
- Bacteria that cause dental caries (cavities)
- Medicated mouthwash
- A liquid that contains medicinal ingredients and is used to rinse the mouth
ResearchResearch themes
Focusing on diseases influenced by periodontopathic and cariogenic bacteria, the lab investigates the correlation between patients' oral environment and systemic condition. It examines the effects of oral bacteria on systemic diseases from both basic and clinical perspectives.
*Illustrative imageThe relationship between diabetes and oral bacteria
The lab investigates how periodontopathic bacteria in the mouth and diabetes markers change when patients with diabetes use a medicated mouthwash.
*Illustrative imageThe relationship between chronic kidney disease and oral bacteria
The lab investigates how a medicated mouthwash affects periodontopathic bacteria, cariogenic bacteria, and systemic condition in patients with chronic kidney disease.
MembersFaculty
The members of the Oral-Systemic Connection Joint Research Lab consist of faculty, project researchers, and visiting faculty.
- Professor (Concurrent)Kazuhiko Nakano
- Associate Professor (Concurrent)Rena Okawa
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “In a dental clinic, New Orleans, 2 April 2026 - 2” Infrogmation / CC BY-SA 4.0 (cropped)
- The relationship between diabetes and oral bacteria: “My Own Oral Mucosa Cells” Ariany Figueiredo dos Santos / CC BY 4.0 (cropped)
- The relationship between chronic kidney disease and oral bacteria: “Chronic kidney disease” Lee, K.-H.; Ho, Y.; Tarng, D.-C / CC BY 4.0 (cropped)
- Related lab (AI Research Unit): “OPG w56J” Couraco / CC BY-SA 3.0 (cropped)
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