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創薬標的探索学分野
Showing the original Japanese · View translation
抗体医薬の創薬ターゲット探索と基盤技術を開発する研究室。
AboutAbout the lab
次世代のバイオ医薬品へ、基盤技術を開発する。
創薬標的探索学分野は、
とくに、
医薬基盤・健康・栄養研究所の
研究室の
研究内容は、
Key terms
- 創薬ターゲット
- 薬が
働きかける 相手に なる 分子。 抗体医薬では、 病態組織の 細胞膜に ある 膜タンパク質が 重要に なる - エピトープ
- 抗体が
結合する、 抗原の 部分。 抗原の 持つ機能と 相関し、 機能性抗体を 作る 手が かりに なる - ADC
- 抗体と
薬物を 結びつけた 複合体。 がんに 薬物を 届ける 技術と して 開発が 進む
ResearchResearch themes
難治性がんなど、
*Illustrative image抗体医薬の標的を探す技術
新しい
*Illustrative image新しい形の抗体誘導体
抗体を
*Illustrative imageエピトープに着目した抗体の解析
抗体が
*Illustrative imageファージ表面提示法でライブラリ作製
ファージ表面提示法で、
MembersFaculty
創薬標的探索学分野の
- Visiting Professor鎌田 春彦
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Monoclonal antibodies (3)” Linda Bartlett (Photographer) / Public domain (cropped)
- 抗体医薬の
標的を 探す 技術: “Antibody-drug conjugate” Bioconjugator / CC BY-SA 4.0 (cropped) - 新しい
形の 抗体誘導体: “Cetuximab” Oguenther at German Wikipedia / Public domain (cropped) - エピトープに
着目した抗体の 解析: “Epitope-mapping illustration-6-copy” Kathryn Edmondson (as employee of Integral Molecular) / CC BY-SA 4.0 (cropped) - ファージ表面提示法で
ライブラリ作製: “Phage display” Thomas Shafee / CC BY 4.0 (cropped)
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