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Gastroenterological Surgery I Lab
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A gastroenterological surgery lab that links the mysteries of cancer development and characteristics to treatment.
AboutAbout the lab
Linking the mysteries of cancer development and characteristics to treatment
The Gastroenterological Surgery I Lab aims to unravel the mysteries of cancer development and characteristics and to link them to treatment.
The lab's website introduces clinical care and research as the Department of Gastroenterological Surgery, and its list of members covers the whole department.
In clinical care, the department treats cancers of the esophagus, stomach, colon, liver, biliary tract, and pancreas, and also provides surgical treatment such as liver transplantation, pancreas transplantation, and inflammatory bowel disease.
Key terms
- Cancer stem cells
- Cancer cells that can self-renew, differentiate into diverse cell types, and form tumors even when only a few are present.
- iPS cells
- Cells made by introducing four genes into fibroblasts. They are expected to be a tool for regenerative medicine.
- Adipose-derived stem cells
- Mesenchymal stem cells isolated from subcutaneous fat. The page reports that their self-renewal capacity and multipotency have been confirmed.
ResearchResearch themes
The Gastroenterological Surgery I Lab aims to clarify the mysteries of cancer development and characteristics and to link them to treatment. The research page introduces studies on cancer stem cells, iPS cells, and regenerative medicine using adipose-derived stem cells. Note, however, that the papers cited on that page go only up to 2011, and the content dates from around the 2010s.
*Illustrative imageTreatment research targeting cancer stem cells
Cancer stem cells are cells that can self-renew, differentiate into diverse cell types, and form tumors even when only a few are present. The lab studies these properties in liver cancer and colorectal cancer, aiming to establish new treatments that target cancer stem cells.
*Illustrative imageDeveloping new methods to generate iPS cells
The lab is working on applying microRNAs to iPS cell generation, and has created cells with pluripotency similar to iPS cells using three types of microRNAs. It is also investigating virus-free induction with a reduced number of transduced genes in normal stem cells from the esophagus and colon, and in adipose-derived stem cells.
*Illustrative imageTissue regeneration using iPS cells
Aiming to apply iPS cells to more practical regenerative medicine, the lab is conducting basic research with the goals of regenerating the liver and pancreatic beta cells.
*Illustrative imageRegenerative medicine with autologous adipose-derived stem cells
In a joint study with Cytori, the lab established a method for isolating mesenchymal stem cells from subcutaneous fat and confirmed their self-renewal capacity and multipotency. The page states that preparations are underway for clinical application at Osaka University.
MembersFaculty
The members of the Gastroenterological Surgery I Lab consist of faculty, doctoral students, and hospital staff physicians.As of 2026
- ProfessorHidetoshi Eguchi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Breast surgery in operating room” Tyler Frew MD / CC BY-SA 4.0 (cropped)
- Treatment research targeting cancer stem cells: “3D printed liver model - tumor” Jan Witowski / CC BY-SA 4.0 (cropped)
- Developing new methods to generate iPS cells: “Human embryonic stem cell colony phase” Id711 at English Wikipedia / Public domain (cropped)
- Tissue regeneration using iPS cells: “Ips cells-es” GcG(wpja user) from 2 PD images. de la traducción Pitana / CC BY-SA 4.0 (cropped)
- Regenerative medicine with autologous adipose-derived stem cells: “Marrow Adipocytes are derived from mesenchymal stem cell (MSC) differentiation” File:Marrow Adipocytes are derived from mesenchymal stem cell (MSC) differentiation. .tif: Mstyner derivative work: Guanaco / CC BY-SA 4.0 (cropped)
- Related lab (Hospital Clinical Laboratory Medicine Lab): “Clinical Chemistry Analyzer , Клинички биохемиски анализатор 1” Делфина / CC BY-SA 4.0 (cropped)
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