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Nephrology Lab
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The Nephrology Lab studies kidney diseases from both basic and clinical perspectives.

AboutAbout the lab
Solving clinical questions through basic research, and bringing the findings back to the clinic.
The Nephrology Lab provides clinical care for kidney diseases and conducts research spanning both basic and clinical science.
The lab investigates questions arising in clinical practice through basic research, and applies findings from basic research in the clinic, linking them to drug discovery.
In clinical research as well, the lab generates evidence on clinically important issues such as IgA nephropathy, nephrotic syndrome, and chronic kidney disease, and communicates it to the world.
The lab also puts effort into undergraduate and postgraduate education, aiming to train nephrologists and clinical scientists.
Key terms
- Autophagy
- A mechanism built into cells that breaks down and processes components inside the cell
- Proximal tubule
- The part of the kidney's tubule system, through which the filtrate formed at the glomerulus passes, where substances are reabsorbed
- Chronic kidney disease
- A condition in which kidney function has declined over a long period of time. Abbreviated as CKD
NewsLab news
Held the Kidney Disease Seminar 2026 for medical students and junior residents (10/16)
A Letter by a lab member was published in European Heart Journal
A paper from the lab was selected for the World Kidney Day collection 2026
A lab member received the Best Abstract Award at the World Congress of Nephrology 2026
A lab member received the YIA Award (Excellence Prize) at the Annual Meeting of the Japanese Society of Renal Rehabilitation
ResearchResearch themes
The lab aims to solve questions that arise in the clinic through basic research, and to connect findings from basic research to clinical practice and drug discovery. The research page lists groups such as autophagy, CKD-MBD, epidemiology, clinical research, and immunity and complement, each with its own papers.
View More ↗MembersFaculty
The members of the Nephrology Lab include the professor; staff such as the head of the clinical division and the ward chief; graduate students and hospital staff physicians; members studying abroad; visiting professors; research assistants; and secretaries.As of 2026
- ProfessorYoshitaka Isaka
- Assistant ProfessorYusuke Sakaguchi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Implantable-artificial-kidney-patients-off-dialysis-machines” Katzze.fritz / CC BY-SA 4.0 (cropped)
- The Role of Autophagy in the Kidney: “Kidney tubules” Katshutko / CC BY 4.0 (cropped)
- Related lab (Psychiatry Lab): “Brain CT Scan for Stroke Diagnosis” Goleisureintl / CC BY 4.0 (cropped)
- Related lab (Advanced AI Medicine Lab): “CSIRO ScienceImage 2465 Sequencing DNA” Health Sciences and Nutrition, CSIRO / CC BY 3.0 (cropped)
- Related lab (Obstetrics and Gynecology Lab): “Retroverted uterus in pregnancy” Mikael Häggström. When using this image in external works, it may be cited as: Häggström, Mikael (2014). "Medical gallery of Mikael Häggström 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.008. ISSN . Public Domain. or By Mikael Häggström, used with permission. / CC0 (cropped)
- Related lab (Endocrinology and Metabolism Lab): “Inzulínová pera” Mr Hyde at Czech Wikipedia (Original text: moje foto) / Public domain (cropped)
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