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Interdisciplinary Group (Nuclear Function) Lab
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A lab that investigates the mechanisms of chromosomal DNA replication.
AboutAbout the lab
Making, transmitting, and protecting chromosomes
The Interdisciplinary Group (Nuclear Function) studies the mechanisms by which chromosomal DNA is replicated.
The lab's website lists "replication licensing," which ensures that chromosomal DNA is replicated only once per cell cycle, as one of the pillars of its research.
In addition to studying replication from the perspectives of making, transmitting, and protecting chromosomes, the lab also lists the development of the "protein interference method," which degrades target proteins to study their functions.
Key terms
- Replication licensing
- A mechanism that ensures chromosomal DNA is replicated only once per cell cycle
- Protein interference method
- A method that degrades a target protein under specified conditions in order to study the function of that protein
ResearchResearch themes
The lab investigates chromosomal DNA replication from several aspects: preparation for replication, initiation of replication, handover of chromosomes, and monitoring of replication abnormalities. It also says it is working on developing methods to study the functions of proteins in cells.
View More ↗MembersFaculty
- Associate ProfessorYumiko Kubota
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Yeast cells in wet mount of culture” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Genome-Chromosome Function Lab): “Independent assortment” Christinelmiller / CC BY-SA 4.0 (cropped)
- Related lab (Interdisciplinary Group (Developmental Biology) Lab): “Fluorescence microscopy of stage 24 squid embryo with ZEISS Celldiscoverer )” ZEISS Microscopy from Germany / CC BY 2.0 (cropped)
- Related lab (Chromosome Structure and Function Lab): “Human karyotype (248 27) Human karyotype” Doc. RNDr. Josef Reischig, CSc. / CC BY-SA 3.0 (cropped)
- Related lab (Plant Physiology Lab): “Photosynthesis System analysing a maize leaf” Viséan / CC BY-SA 4.0 (cropped)
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