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Quantum Measurement Lab
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A lab that explores nanomaterials and biomolecules using ultrasound and optical measurement techniques.
AboutAbout the lab
Probing nanomaterials and biomolecules with sound and light measurement
The Quantum Measurement Lab uses its original ultrasound and optical measurement techniques to study nanomaterials and biomolecules and to develop new devices.
The ultrasound frequencies it works with span a wide range, from 20 kHz to 1 THz, and the target materials vary as well.
The lab works on protein quantification devices that contribute to diagnosis and drug discovery, research on applying force to cells, and sensors for assessing the structural health of social infrastructure.
On the lab's website, it is introduced under the name "Ogi Lab."
Key terms
- Ultrasound
- Sound with a frequency of 20 kHz or higher, which humans cannot hear
- Amyloid fibril
- A needle-like aggregate, similar to a crystal, formed by denatured proteins. It is a causative agent of diseases such as Alzheimer's disease.
- Mechanobiology
- A research field that studies the relationship between forces acting on cells and cell function
NewsLab news
A paper on a wireless acoustic sensor was accepted and selected as an Editors' Suggestion
A paper from a collaborative study measuring the stiffness of biomolecular droplets with acoustic tweezers was accepted by PRX Life
A doctoral student won a Poster Award at the 26th Annual Meeting of the Protein Science Society of Japan
A doctoral student received the Mutsumi Award from the Japanese Society for Non-Destructive Inspection
ResearchResearch themes
The Quantum Measurement Lab uses its original phonon and optical measurement to study nanomaterials and biomolecules and to develop new devices. The ultrasound frequencies it handles span a very wide range, from 20 kHz to 1 THz, and the research also incorporates AI techniques developed in-house.
*Illustrative imageBiosensors
The lab develops devices and sensors for examining protein reactions, contributing to early detection of intractable diseases and development of new drugs. These include a reaction analyzer with "eyes and ears," a label-free, highly sensitive sensor that can be used almost permanently, and wireless, electrodeless sensors.
*Illustrative imageAcceleration of protein aggregation by ultrasound
The lab studies the phenomenon in which ultrasound speeds up protein aggregation, aiming to identify the causes of intractable diseases. It is working to elucidate how the formation of amyloid fibrils, aggregates made by denatured proteins, is accelerated.
*Illustrative imageCell mechanobiology
This research aims to clarify the relationship between forces acting on cells and cell function. The lab is developing a system that applies mechanical stimulation by ultrasound, without contact, to the nuclei of cultured adherent cells, and an AI ultrasound microscope that can observe living cells at high resolution over long periods.
*Illustrative imageAcoustic electronic devices
This research on acoustic electronic devices aims to contribute to dramatic advances in next-generation mobile communication equipment. Using Brillouin oscillations, the lab examines phonons in thin films of functional semiconductors and oxides.
MembersFaculty
The members of the Quantum Measurement Lab consist of faculty, project researchers, visiting professors and visiting researchers, doctoral, master's, and undergraduate students, and administrative assistants.As of 2026
- ProfessorHirotsugu Ogi
- Associate ProfessorKichitaro Nakajima
- Assistant ProfessorNatsumi Fujiwara
- Assistant ProfessorYasushi Oshikane
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Unreaviling water surface” Pawel Nowakowski / CC BY-SA 4.0 (cropped)
- Biosensors: “DNA microarray chip” ErikAbner / CC BY 4.0 (cropped)
- Acceleration of protein aggregation by ultrasound: “Mechanisms of amyloid fibril formation” Pierre Hugots / CC BY-SA 4.0 (cropped)
- Cell mechanobiology: “Indian Muntjac fibroblast cells ( )” ZEISS Microscopy from Germany / CC BY 2.0 (cropped)
- Acoustic electronic devices: “F1319M SAW Filter” Mister rf / CC BY-SA 4.0 (cropped)
- Related lab (Nanospectroscopy Lab): “Optical cell rotator” Katzeimsack72 / Public domain (cropped)
- Related lab (Atomic Process Control Lab): “Scanning tunneling microscope-MHS 2237-IMG 3816” Rama / CC BY-SA 3.0 fr (cropped)
- Related lab (Nanophotonics Lab): “InVia Raman microscope - March 2008” theterrifictc / CC BY-SA 2.0 (cropped)
- Related lab (Surface Nanoscale Properties Lab): “Scanning tunneling microscope-MHS 2237-IMG 3817-black” Rama / CC BY-SA 3.0 fr (cropped)
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