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Biomolecular Organization Chemistry Lab
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The lab assembles biomolecules to turn carbon dioxide into a resource.
AboutAbout the lab
Learning from how living organisms work to turn carbon dioxide into a resource.
The Biomolecular Organization Chemistry Lab (Nakata Lab) is a new lab that started in April 2025. It develops chemical methods for organizing biomolecules and explores the new functions that emerge from organizing them.
Making use of the energy utilization systems of living organisms, centered on enzymes, the lab organizes biomolecules for specific purposes to build new material conversion systems that use carbon dioxide as a resource, aiming to achieve 'carbon negative' through biological approaches.
Key terms
- Enzyme
- A protein that drives chemical reactions inside living organisms
- DNA nanostructure
- A nanoscale structure made by folding DNA according to a design
- Metabolism
- The flow of chemical reactions that build up and break down substances inside living organisms
ResearchResearch themes
Modeled on the energy utilization systems of living organisms, the lab controls chemical reactions in organisms at each scale, aiming to realize clean and highly efficient energy utilization systems.
*Illustrative imageEngineering carbon dioxide-fixing metabolism
Focusing on metabolic reactions that fix carbon dioxide among the chemical reactions in living organisms, the lab aims to engineer those reactions to synthesize valuable, useful substances.
*Illustrative imageA molecular industrial complex of arrayed enzymes
Using DNA nanostructures as scaffolds, the lab arranges proteins, enzymes, and nucleic acids at targeted positions to build a 'molecular industrial complex' in which multistep reactions proceed as efficiently as metabolism inside cells, aiming for an artificial metabolic system that works outside cells.
*Illustrative imageFluorescent sensors inside cells
The lab creates fluorescent sensors that make metabolic reactions visible, using methods from synthetic chemistry and genetic engineering. It is also building a mechanism that gathers multiple sensors on a scaffold to detect several targets at the same time.
MembersFaculty
- ProfessorEiji Nakata
- Assistant ProfessorARAFILES Jan Vincent
- Assistant ProfessorLIN Peng
- Program-Specific Assistant ProfessorMorito Sakuma
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “DNA nanostructures” (Images were kindly provided by Thomas H. LaBean and Hao Yan.) / CC BY 2.5 (cropped)
- Engineering carbon dioxide-fixing metabolism: “Calvin cycle diagram miguelferig” Miguelferig / CC0 (cropped)
- A molecular industrial complex of arrayed enzymes: “DNA Origami” Origamimonkey / CC BY-SA 3.0 (cropped)
- Fluorescent sensors inside cells: “Abnormal transfected HEK 293 cell” Borys Olifirov / CC BY 4.0 (cropped)
- Related lab (Molecular Nanoengineering Lab): “B-doped graphene nanoribons” Shigeki Kawai et al. / CC BY 4.0 (cropped)
- Related lab (Energy Structural Life Science Lab): “Wood decay mushrooms” Sindugab / CC0 (cropped)
- Related lab (Green Catalysis and Chemical Conversion Lab): “Catalyst for hydrogenation ( )” Максим Фомич / CC BY 2.0 (cropped)
- Related lab (Functional Properties Engineering Lab): “Types of Carbon Nanotubes” User Mstroeck on en.wikipedia / CC BY-SA 3.0 (cropped)
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