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Food Physiology and Function Lab
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A lab that uses the power of food to ease fatigue, stress, and obesity and to improve quality of life.
AboutAbout the lab
Putting the functions of food to work for a better quality of life.
The lab studies how food components affect the body's regulatory mechanisms, at the levels of the whole organism, organs, cells, genes, and molecules.
It aims to determine what foods are truly desirable for preventing lifestyle-related diseases and for maintaining and promoting health.
Undergraduates are assigned to the lab in their fourth year (graduate students belong to the Division of Food Science and Biotechnology, Graduate School of Agriculture).
Key terms
- Peptide
- A short chain of several amino acids, produced when proteins are broken down
- Optogenetics
- A method that uses light to switch specific neurons on and off in order to study their roles
- Metabolome analysis
- A method for comprehensively analyzing the metabolites in the body all at once
ResearchResearch themes
The lab aims to ease problems such as fatigue, stress, and obesity through the functions of foods, their components, and peptides produced by protein breakdown, and thereby to improve quality of life (QOL). It investigates how food affects the nervous system, the digestive system, and the circulatory system.
*Illustrative imageExercise, fatigue, and the mechanism of motivation
Using physiology, optogenetics, and other methods, the lab investigates how the brain regulates energy use during exercise, how motivation arises and is sustained, and how fatigue occurs, aiming to develop foods that prevent and relieve fatigue.
*Illustrative imageFood peptides that act from the gut on the brain
The lab has developed a method to efficiently identify the active substances among the vast number of molecules produced when food components are broken down, and has found new compounds that raise motivation, relieve stress, and lower blood glucose and blood pressure.
*Illustrative imageObesity and sugar and lipid metabolism
Obesity underlies many lifestyle-related diseases. The lab aims to elucidate how obesity and sugar and lipid metabolism are regulated, and to establish methods that use the functions of food to prevent and improve lifestyle-related diseases.
*Illustrative imageAnalyzing metabolites comprehensively
Using metabolome analysis with LC-MS, the lab comprehensively examines food components, their changes in the body, and their effects on sugar and lipid metabolism, which is closely tied to disease.
MembersFaculty
The lab's members include faculty, part-time administrative staff, project researchers, postdoctoral researchers, and researchers, as well as doctoral, master's, and undergraduate students.
- ProfessorKazuo Inoue
- Associate ProfessorKosaku Ohinata
- Associate ProfessorTsuyoshi Goto
- Assistant ProfessorHaruya Takahashi
- Assistant ProfessorTakumi Yokokawa
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Food-healthy-vegetables-potatoes ( )” www.Pixel.la Free Stock Photos / CC0 (cropped)
- Exercise, fatigue, and the mechanism of motivation: “Exercise Treadmill Convey Motion” Larry D. Moore / CC BY 4.0 (cropped)
- Food peptides that act from the gut on the brain: “Peptide model s” Peter Murray-Rust / CC BY-SA 2.5 (cropped)
- Obesity and sugar and lipid metabolism: “Blausen 0012 AdiposeTissue” BruceBlaus. When using this image in external sources it can be cited as: Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN . / CC BY 3.0 (cropped)
- Analyzing metabolites comprehensively: “LC MS pic” US gov / Public domain (cropped)
- Related lab (Bioorganic Chemistry Lab): “Chemical Compound ( )” National Center for Advancing Translational Sciences from Bethesda, MD / Public domain (cropped)
- Related lab (Molecular Biology and Bioresponse Lab): “Zinc foils” Mauro Cateb / CC BY-SA 3.0 (cropped)
- Related lab (Agricultural Product Manufacturing Lab): “Production of cheese 1” MatthiasKabel / CC BY-SA 3.0 (cropped)
- Related lab (Nutritional Chemistry Lab): “Japanese set meal with tonkatsu” Betsylavolette / CC BY-SA 4.0 (cropped)
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