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Molecular Biological Information Lab
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The lab explores the evolution and mechanisms of light-sensing proteins.
AboutAbout the lab
Reading the path of evolution from light-sensing proteins.
The Molecular Biological Information Lab seeks to understand the essence of proteins by combining three pillars: molecular evolution, physiological function, and molecular mechanisms.
As a model, the lab focuses on photoreception in animals.
Centering on rhodopsin, the photoreceptor protein of the retina, the lab analyzes the molecular basis of the diversity of photoreceptive functions using spectroscopy, biochemistry, molecular biology, and electrophysiology.
Key terms
- Rhodopsin
- A protein in the retina that receives light. It initiates vision.
- G protein-coupled receptor
- A family of receptors located in the cell membrane that receive signals from outside the cell and relay them inside.
- Molecular evolution
- How molecules such as DNA and proteins have changed over the course of evolution.
ResearchResearch themes
With vision, G protein-coupled receptors, and photophysiology as research themes, the lab conducts research that combines the molecular evolution, physiological function, and molecular mechanisms of proteins.
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MembersFaculty
The members of the Molecular Biological Information Lab are faculty members, researchers, master's students, fourth-year undergraduates, and technical assistants.As of 2026
- ProfessorMasataka Yanagawa
- Associate ProfessorYasushi Imamoto
- LecturerTakahiro Yamashita
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Mouse cone and rabbit rod nuclei” Irina Solovei, Moritz Kreysing, Christian Lanctôt, Süleyman Kösem, Leo Peichl, Thomas Cremer, Jochen Guck, Boris Joffe / CC BY 2.5 (cropped)
- Diversity of Photoreceptive Functions: “FDTD model of light scattering by photoreceptor nucleus” Irina Solovei, Moritz Kreysing, Christian Lanctôt, Süleyman Kösem, Leo Peichl, Thomas Cremer, Jochen Guck, Boris Joffe / CC BY 2.5 (cropped)
- Related lab (量子化学研究室): “Amniote rhodopsin 3D structures” Constanze Bickelmann / CC BY-SA 3.0 (cropped)
- Related lab (Theoretical Biophysics Lab
（理論生物物理学分科） ): “Schematic of a single-tethered DNA curtain” Soyeong An, Youngseo Kim, and Ja Yil Lee / CC BY 4.0 (cropped) - Related lab (数理生命科学
（望月 敦史） ): “Gene-gene-interaction-network-of-84-genes-upregulated-in-both-PT-and-LM” Zhenyuan Qian, Guobing Zhang, Guangyuan Song, Ji Shi, Lijie Gong, Yiping Mou, Yong Han / CC BY 3.0 (cropped) - Related lab (京都大学 時間生物学グループ): “Synechococcus PCC 7002 DIC” Masur / Public domain (cropped)
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