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Mochizuki Lab
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A lab that uses mathematics to explain biological networks and cell structures.
AboutAbout the lab
Reading the mechanisms of life through mathematical theory
The Mathematical Life Science group (Mochizuki Lab) aims to explain life phenomena that arise from complex biomolecular networks and intracellular structures, using mathematical theory.
The lab has independently developed mathematical theories that determine important aspects of dynamics from network information alone, and it repeatedly alternates between theoretical predictions and experimental verification.
It also models the shapes and movements of organelles, the cytoskeleton, and other structures using methods from statistical physics, soft matter physics, and complex systems science.
Key terms
- Linkage Logic
- A structural theory that can identify a key subset of molecules from the structure of a regulatory network alone
- Organelle
- A small structure inside a cell, such as a mitochondrion or the nucleus
- Soft matter physics
- The branch of physics that studies the behavior of soft materials such as polymers, liquid crystals, and membranes
ResearchResearch themes
The lab studies the dynamics of biomolecular networks and the shape and movement of intracellular structures, using mathematical theory and methods from physics.
*Illustrative imageNetwork Dynamics
The lab has independently developed mathematical theories that determine important aspects of dynamics from network information alone. It applies the structural theory Linkage Logic to real biological networks.
*Illustrative imagePhysics of Intracellular Structures
Structures such as organelles and the cytoskeleton carry out cell functions as many molecules self-organize, assemble, and move in characteristic forms. The lab models their shapes and movements using methods from statistical physics and soft matter physics.
MembersFaculty
- ProfessorAtsushi Mochizuki
- Assistant ProfessorMasato Ishikawa
- Program-Specific Assistant ProfessorSUN Liangjie
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Gene-gene-interaction-network-of-84-genes-upregulated-in-both-PT-and-LM” Zhenyuan Qian, Guobing Zhang, Guangyuan Song, Ji Shi, Lijie Gong, Yiping Mou, Yong Han / CC BY 3.0 (cropped)
- Network Dynamics: “Gene Regulatory Network” 作者不詳 / Public domain (cropped)
- Physics of Intracellular Structures: “Eukayotic Cell (430x maginification)” Jlipuma1 / CC BY 4.0 (cropped)
- Related lab (Active Matter Lab): “DNA Origami Triangular” Matthias A. Fenner / CC BY-SA 4.0 (cropped)
- Related lab (Statistical Physics and Dynamics Lab): “Phase separation in Kupchan partitioning” Ikramul Hasan Imran / CC BY 4.0 (cropped)
- Related lab (Plant Systematics and Taxonomy Lab): “Ranunculus lingua herbarium specimen by Joseph Witry” Musée national d'histoire naturelle Luxembourg / CC BY 4.0 (cropped)
- Related lab (Computer Science (Programming Language Theory, Distributed Computing Theory) Lab (Susumu Nishimura)): “SimplexTree” Vibass / CC BY-SA 4.0 (cropped)
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