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Frommer Lab
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A research group exploring how substances are transported in plant cells.

AboutAbout the lab
Exploring how plant cells transport substances
The Frommer Lab studies how proteins that transport substances in plant cells are positioned and how they function.
The lab works on the mechanisms of cell polarity, in which proteins are asymmetrically localized at the cell surface, and on developing biosensors that measure sugars and plant hormones.
Together with other groups at ITbM, the lab also investigates how membrane transporters, which carry substances across membranes, select the substances they transport.
Key terms
- Cell polarity
- A phenomenon in which proteins are asymmetrically localized on one side of the cell surface
- Transporter
- A protein that transports nutrients, plant hormones, and other substances
- Biosensor
- A tool that uses fluorescent proteins to measure the amounts of sugars, plant hormones, and other molecules
ResearchResearch themes
The lab investigates how proteins are asymmetrically positioned at the surface of plant cells and which substances membrane transporters select to transport. It also develops tools for studying molecules inside cells, using fluorescent proteins and small fluorescent molecules.
*Illustrative imageMechanisms of plant cell polarity
The lab studies how transporters that carry nutrients and plant hormones, among other proteins, are asymmetrically localized at the cell periphery. Using the borate transporter BOR1 and others as models, it is searching for the targets of small-molecule compounds that inhibit cell polarity.
*Illustrative imageBiosensors for measuring molecules
Using fluorescent proteins, the lab develops biosensors that quantify biomolecules such as sugars and plant hormones. In collaboration with chemistry groups at ITbM, it also develops imaging tools based on small fluorescent molecules.
*Illustrative imageSubstrate selectivity and inhibitors of membrane transporters
In collaboration with other groups at ITbM, the lab investigates the molecular mechanisms by which membrane transporters that handle multiple substrates choose which substances to transport. It identifies inhibitors of membrane transporters and develops them into molecules that can be applied to agricultural research.
MembersFaculty
The members of the Frommer Lab are faculty, postdoctoral researchers, technicians, technical assistants, and secretaries.
- ProfessorWolf Frommer
- Associate ProfessorSatomi Kanno
- Project LecturerAkira Yoshinari
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Red onion cells (microscope observation)” Edoardo Simon / CC BY-SA 4.0 (cropped)
- Mechanisms of plant cell polarity: “Observation of the plasma membrane during plasmolysis in Rhio leaf cells” Krishna satya 333 / CC BY-SA 4.0 (cropped)
- Biosensors for measuring molecules: “Green fluorescent protein (GFP) in Eppendorf Tubes” Juan Carlos Fonseca Mata / CC BY-SA 4.0 (cropped)
- Substrate selectivity and inhibitors of membrane transporters: “Molecular model of the pre-pore form of a MACPF protein based upon the structure of pneunolysin” Jcwhizz at English Wikipedia / CC BY-SA 3.0 (cropped)
- Related lab (Bodeグループ): “Bureau of Chemistry Carbohydrate Laboratory - DPLA - 393369f3413bba4840a90435375d72e9” United States. Food and Drug Administration / Public domain (cropped)
- Related lab (栗原グループ): “Plant cell - ben” Benjaminphanijchanont / CC BY 4.0 (cropped)
- Related lab (
大井グループ): “Laboratory synthesis of Protectin D1 (PD1)” Papik1988 / CC BY-SA 3.0 (cropped) - Related lab (木下グループ): “Tomato leaf stomate 1-color” Photohound / Public domain (cropped)
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