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Medical Functional Imaging Evaluation Lab
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A nuclear medicine lab that uses radiopharmaceuticals and imaging technology to visualize how the body functions.

AboutAbout the lab
Visualizing the body's functions to contribute to diagnosis and treatment.
The Medical Functional Imaging Evaluation Lab (Nishii Lab and Hirano Lab) centers on nuclear medicine, and its research spans the development of radiopharmaceuticals, the acquisition and analysis of images, and the elucidation of the effects of radiation.
Nuclear medicine is a medical field that uses radioactive isotopes to visualize functions and metabolism in the body for diagnosis and treatment.
Through the development of radiopharmaceuticals that target specific molecules and disease conditions, and of high-performance cameras, the lab conducts research that contributes to both diagnosis and treatment.
As the concept of "theranostics," which integrates diagnosis and treatment, becomes more widespread, the lab also works on AI-based image analysis and on elucidating how radiation affects cells.
Key terms
- Nuclear medicine
- A medical field that uses radioactive isotopes to visualize functions and metabolism in the body for diagnosis and treatment
- Theranostics
- An approach that uses radiopharmaceuticals to integrate diagnosis and treatment
- Patient-specific dosimetry
- A method of assessing absorbed doses to tumors and normal organs based on the distribution of a radiopharmaceutical in each patient
NewsLab news
A paper by lab faculty was published in Journal of Instrumentation
A paper by lab faculty was published in Phys. Med. Biol.
A paper by Associate Professor Hirano and colleagues was published in Physica Scripta
A master's student received the Judges' Encouragement Award at the 5th Health Science Research Meeting
ResearchResearch themes
Drawing on the characteristics of nuclear medicine, the lab advances research from basic studies through to clinical application. Its work includes the development of radiopharmaceuticals, the development of imaging devices and cameras, AI-based image analysis, and the elucidation of how radiation affects cells, with themes that vary by faculty member.
*Illustrative imageNuclear Medicine Imaging and Radioisotope Therapy
The lab works on molecular imaging, clinical nuclear medicine imaging for diagnosis, targeted radioisotope therapy, AI-based tumor image analysis, the development of new radiopharmaceuticals such as amino acid PET tracers, and image-based radiation dose assessment.
*Illustrative imageEffects of Radiation on DNA and Cells
The lab investigates the connections from the atomic and molecular levels, where the initial processes of radiation effects occur, up to the cellular level, using simulations of DNA damage structures, analysis of gene expression after irradiation, and time-lapse observation of cells.
*Illustrative imageDevelopment of New Imaging Systems
The lab is developing and applying portable gamma cameras, imaging small animals using Cherenkov light, improving the quantitative accuracy of clinical gamma cameras, applying flexible scintillators to dosimetry, and developing excitation and imaging systems for near-infrared fluorescence.
*Illustrative imageDosimetry and Imaging Technology in Nuclear Medicine
In nuclear medicine therapy, the lab studies methods of patient-specific dosimetry, using SPECT/CT and PET/CT to quantitatively assess absorbed doses to tumors and normal organs. It also examines imaging conditions and image reconstruction techniques that improve the image quality and quantitative accuracy of PET and SPECT.
MembersFaculty
The members of the Medical Functional Imaging Evaluation Lab consist of faculty and master's and undergraduate students.As of 2026
- ProfessorRyuichi Nishii
- Associate ProfessorYoshiyuki Hirano
- Assistant ProfessorKohei Nakanishi
- Assistant ProfessorYuto Kamitaka
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “A nuclear medicine machine is used for medical imaging in a hospital in North Carolina 04” Harrison Keely / CC BY 4.0 (cropped)
- Nuclear Medicine Imaging and Radioisotope Therapy: “Doctors Memorial Hospital Transport and Nuclear Medicine Therapy and Imagery (20240318-USDA-RD-FL-LSC-8910)” USDAgov / Public domain (cropped)
- Effects of Radiation on DNA and Cells: “DNA double helix 45” Jerome Walker,Dennis Myts / Public domain (cropped)
- Development of New Imaging Systems: “Radiacode 102” Mykhal / CC0 (cropped)
- Dosimetry and Imaging Technology in Nuclear Medicine: “Moderní výpočetní tomografie s přímo digitální detekcí rentgenového záření” Tomáš Vendiš / CC BY-SA 4.0 (cropped)
- Related lab (Biomolecular Information Science Lab): “Agilent 1200HPLC and 6130 MS” Nick Birse / CC BY-SA 4.0 (cropped)
- Related lab (Medical Quantum Science Lab): “UW Therapy room” Ikiwaner / CC BY-SA 3.0 (cropped)
- Related lab (Medical Imaging Engineering Lab): “Model positioned in computed tomography scanner” Daniel Sone (Photographer) / Public domain (cropped)
- Related lab (Host Defense Information Science Lab): “Tingible body macrophage” Arnold, Michael A.; Kahwash, Samir B. / CC BY 3.0 (cropped)
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