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Dermatology (Pathophysiology of Skin Diseases) Lab
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The Department of Dermatology turns clinical questions from the care of hereditary skin diseases, connective tissue diseases, and skin tumors into research.
AboutAbout the lab
Beyond the skin: disease mechanisms, the whole body, and the future.
The department carries out clinical care and research around three teams: hereditary skin diseases and keratinization disorders, connective tissue diseases, and skin tumors.
It aims to connect questions arising from patient care to research in genetics, immunology, and oncology, and to deliver the results to patients as new diagnostics and treatments.
Since its founding in 1905, the department has supported dermatological care, medical education, and research in the Tokai region.
The department accepts dermatology observerships from medical students, junior residents, and residents in specialty training on a rolling basis.
Key terms
- Connective tissue diseases
- A group of diseases that includes systemic sclerosis, dermatomyositis, and Sjögren's syndrome
- Autoantibody
- An antibody produced against a patient's own body components. Serum is examined and used for diagnosis and understanding of disease mechanisms
- Autoinflammatory keratinization diseases
- A group of diseases in which autoinflammation and abnormal keratinization are closely linked
NewsLab news
A paper by Assistant Professor Yamashita et al. was published in Rheumatology (Oxford, England)
A paper by Assistant Professor Yamashita et al. was published in RMD open
Associate Professor Takeichi received the "Top Reviewer Awards 2023 in the Journal of Dermatology"
A paper by Associate Professor Tanahashi et al. was published in The British journal of dermatology
Associate Professor Takeichi received the "Sun Pharma RISING SUN AWARD 2023" (Japanese Society for Investigative Dermatology)
ResearchResearch themes
The department's research policy is to connect problems arising from patient care to elucidating disease mechanisms and developing new treatments. The hereditary skin disease and keratinization disorder team and the connective tissue disease team conduct both clinical and basic research, while the skin tumor team focuses on clinical research directly tied to patient care.
*Illustrative imageHereditary Skin Diseases and Keratinization Disorders
The team studies rare, intractable hereditary skin diseases, such as epidermal differentiation disorders, autoinflammatory keratinization diseases, and congenital hypotrichosis. Starting from clinical information and genetic analysis, it aims to understand disease mechanisms and develop new treatments.
*Illustrative imageAutoantibody Analysis in Connective Tissue Diseases
Targeting systemic sclerosis, dermatomyositis, Sjögren's syndrome, and other diseases, the team uses molecular biology methods to analyze autoantibodies in patients' serum and the antigens they target. The findings feed into diagnosis and understanding of disease mechanisms.
*Illustrative imageClinical Research on Skin Tumors
Targeting malignant melanoma, squamous cell carcinoma, extramammary Paget's disease, angiosarcoma, and other tumors, the team covers everything from surgery to systemic therapy and genomic medicine. It develops problems from daily practice into clinical research.
MembersFaculty
The members of the department are faculty, staff physicians, and graduate students.As of 2026
- ProfessorTakuya Takeichi
- Associate ProfessorKana Tanahashi
- LecturerMariko Momohara
- Assistant ProfessorShoichiro Mori
- Assistant ProfessorTakenori Yoshikawa
- Assistant ProfessorYuta Yamashita
- Hospital Assistant ProfessorYuika Suzuki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “IDS-1100 Dermatoscope” Abessemans94 / CC BY-SA 4.0 (cropped)
- Hereditary Skin Diseases and Keratinization Disorders: “DNA double helix horizontal” Jerome Walker / Public domain (cropped)
- Autoantibody Analysis in Connective Tissue Diseases: “Immunofluorescence light microscopy I” Juan Carlos Fonseca Mata / CC BY-SA 4.0 (cropped)
- Clinical Research on Skin Tumors: “Histopathology of melanoma, HE” Robert M. Hurwitz, Larry J. Buckel, Don-John Summerlin / CC BY 4.0 (cropped)
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