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Cellular and Molecular Informatics Lab
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A lab that connects cells, molecules, and information through engineering, aiming to put drug discovery and regenerative medicine into practical use.
AboutAbout the lab
Aiming for digital transformation in cell manufacturing.
The Cellular and Molecular Informatics Lab connects cells, molecules, and information from an engineering perspective, and studies practical technologies that support drug discovery and regenerative medicine.
The lab runs research themes in three areas: regenerative medicine, drug discovery screening, and medical device development.
Each member learns both experimental skills, such as cell culture and gene analysis, and computational skills, such as image analysis and statistical analysis, while doing research.
Through joint research with people from many fields, such as physicians and companies, the lab aims to do research that leads to manufacturing (monozukuri).
Key terms
- iPS cells
- Cells made from skin or blood cells that can develop into many different types of cells in the body
- Phenotypic screening
- A method of giving drug candidates to cells and finding the ones that work, using changes in cell shape and properties as clues
- Spheroid
- A small, ball-like three-dimensional cluster of cells. It can reproduce a state close to that of tissue in the body
NewsLab news
A doctoral student received the Frontier Award (LADEC Awards) at LADEC 2026
A master's student received the Dean's Award of the Graduate School
A master's student received the Young Researcher Encouragement Award at the 16th Screening Science Research Meeting
A master's student received an Excellent Presentation Award at the CBI Society meeting
Joint research with the University of Tokyo and Osaka University digitalizes process design for stem cell culture (Communications Biology)
ResearchResearch themes
The lab's goal is DX (digital transformation) in cell manufacturing. It connects biology, which deals with cells, chemistry, which deals with molecules, and data science, which deals with information, from an engineering perspective, and carries out research in five projects.
*Illustrative imageEvaluating quality from cell images
The lab builds technologies that analyze cell shape information from images to evaluate cell quality, as well as the foundation for a cloud-based evaluation system. It also uses image analysis to evaluate automated culture of iPS cells and to quantify the manual techniques and work efficiency of people who culture cells.
*Illustrative imageSearching for drugs by cell shape
The lab develops phenotypic screening technologies that use cell shape information. It also works on informatics methods for analyzing neurons, and on image analysis for evaluating drug toxicity in cardiomyocytes derived from iPS cells.
*Illustrative imageExamining spheroids without destroying them
The lab develops a system that uses near-infrared imaging to evaluate spheroid quality without destroying the spheroids, together with the imaging devices and software for it. It also uses image analysis to evaluate cancer spheroids and to monitor organoid culture.
*Illustrative imageDesigning the surfaces of medical devices
The lab works on the surface design of medical devices, including materials that combine peptides and polysaccharides for artificial blood vessels, sheets that prevent adhesion, and materials that promote bone regeneration. It designs surfaces that promote regeneration using short peptides, and examines their functions through informatics analysis.
MembersFaculty
The members of the Cellular and Molecular Informatics Lab are faculty members, technical assistants, and doctoral, master's, and undergraduate students.As of 2026
- Associate ProfessorRyuji Kato
- Assistant ProfessorKenjiro Tanaka
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Biotechnology lab” Timothydotuns / CC BY-SA 4.0 (cropped)
- Evaluating quality from cell images: “Mesothelioma cultured cells from pleural effusion AO AL 5” Federica Viazzi (AO AL) / CC BY-SA 4.0 (cropped)
- Searching for drugs by cell shape: “Neuron in tissue culture” GerryShaw / CC BY-SA 3.0 (cropped)
- Examining spheroids without destroying them: “Co-culture spheroid of HT1376 and RT112 cells” Altyn0707 / CC BY 4.0 (cropped)
- Designing the surfaces of medical devices: “Laboratory of Biomaterials” Berillo D / CC BY-SA 4.0 (cropped)
- Related lab (化学遺伝学研究グループ): “Pipetten” No machine-readable author provided. Newbie~commonswiki assumed (based on copyright claims). / Public domain (cropped)
- Related lab (分子設計化学分野): “Verrerie de Souvigny 04” Laurajwilkinson / CC BY-SA 4.0 (cropped)
- Related lab (超分子設計学研究グループ): “Photoluminescent rhodium coordination complex crystals under UV light” RhAgchem / CC BY-SA 4.0 (cropped)
- Related lab (生体分子応用化学研究グループ): “Coronavirus. SARS-CoV-2” Alexey Solodovnikov (Idea, Producer, CG, Editor), Valeria Arkhipova (Scientific Сonsultant) / CC BY-SA 4.0 (cropped)
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