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Takahashi Lab
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The lab advances cancer treatment using light and radiation.
AboutAbout the lab
Putting light and radiation to work against cancer.
The Takahashi Lab studies biomedical engineering, applying light and radiation technologies to medicine.
Photodynamic therapy is a cancer treatment that uses a photosensitizer, which produces reactive oxygen species and also emits fluorescence when exposed to light.
Recently, it has become clear that certain organic compounds produce reactive oxygen species when exposed to radiation.
Using such compounds as radiosensitizers is thought to lead to treatments for cancers that respond poorly to radiation.
Key terms
- Photodynamic therapy
- A treatment that uses a drug activated by light to target and destroy cancer cells
- Photosensitizer
- A drug that absorbs light and converts surrounding oxygen into a more reactive form
- Reactive oxygen species
- Forms of oxygen that are more reactive than ordinary oxygen and can damage cells
ResearchResearch themes
The Takahashi Lab closely investigates the physicochemical reactions that occur between light or radiation and organic compounds, and the biological responses those reactions cause. In particular, it focuses on protoporphyrin IX induced inside cells by 5-aminolevulinic acid, aiming to clarify how its accumulation and reactivity affect the effectiveness of cancer diagnosis and treatment.
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MembersFaculty
- ProfessorJunko Takahashi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Photodynamic therapy 2” Ed Mkh / CC BY-SA 3.0 (cropped)
- Treating Cancer with Radiation and Drugs: “Linear Accelerator - Elekta Compact model” Narenfox / CC BY-SA 4.0 (cropped)
- Related lab (Tateno Lab): “CSIRO ScienceImage 3719 CSIROs Fleck wireless sensor network technology” Stephan Brosnan, CSIRO / CC BY 3.0 (cropped)
- Related lab (Mawatari Lab): “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Related lab (Shimura Lab): “Semiconductor Wafer of Microelectronics” DrHughManning / CC BY-SA 4.0 (cropped)
- Related lab (Miyake Lab): “Corrective soft contact lenses, with high oxigen permeability” Albarubescens / CC BY-SA 4.0 (cropped)
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