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Sugimoto Lab
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The lab learns from the fundamentals of life to create organic molecules with useful functions.
AboutAbout the lab
Developing functional organic molecules inspired by the fundamentals of life
The Sugimoto Lab takes chemical reactions inside living organisms as a model and studies how to make organic molecules that perform special functions.
The molecules it makes include raw materials that form the basis of products useful in everyday life, and catalysts for the chemical reactions used to produce them.
Researchers carry out their work through repeated trial and error: they design the molecules themselves, make them with their own hands, and improve them over and over.
Research themes include reproducing the action of enzymes with artificial molecules, synthesizing polymers with controlled structures, and synthesizing polymers using carbon dioxide.
Key terms
- Asymmetric synthesis
- Selectively making only the desired one of two molecules that are mirror images of each other (right-handed and left-handed forms)
- Enantiomer
- Isomers that are mirror images of each other, "right" and "left." They are common among biologically active substances, and enzymes in living organisms distinguish between the two forms
- Metal complex
- A compound in which molecules are bound to a metal. In this lab, they are designed and used as catalysts for polymerization reactions
ResearchResearch themes
The Sugimoto Lab takes chemical reactions inside living organisms as a model, and designs and synthesizes organic molecules that perform special functions. By making molecules that serve as raw materials and catalysts, the lab aims to lead to artificial enzymes, new polymer materials, and the chemical utilization of carbon dioxide.
*Illustrative imageChemistry That Surpasses Living Organisms
Functional groups and molecules that have only limited properties on their own can show new performance when several of them come together and are arranged in the right positions. Based on this idea, the lab designs optically active molecules such as artificial enzymes and supramolecular complexes, aiming for asymmetric molecular recognition and asymmetric synthesis.
*Illustrative imageChemistry That Artificially Reproduces Life Phenomena
Enzymes in living organisms distinguish between isomers that are mirror images of each other (enantiomers), and produce only the needed substance with high selectivity and yield. The lab makes functional molecules that mimic the structure of these enzymes, aiming to achieve molecular recognition and catalytic reactions.
*Illustrative imageSynthesis of Polymers with Controlled Structures
Using polymerization reactions catalyzed by metal complexes, the lab aims to develop methods for producing polymers with controlled structures, as well as new polymers that have never been synthesized before. It also tries applying the resulting polymers to functional materials and bio-related polymers.
*Illustrative imagePolymer Synthesis Using Carbon Dioxide
The lab aims to capture and activate carbon dioxide with transition metal complexes and combine it with other monomers to synthesize useful polymer materials. Polymers that contain carbon dioxide in their main chain are expected to have properties such as biodegradability and oxygen permeability.
MembersFaculty
- ProfessorHiroshi Sugimoto
- LecturerMasayoshi Honda
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “HK Central 12 Lan Kwai Fong Rockabilly shop Carbon Dioxide gas bottle Asahi beer Guinness Dec-2015 DSC” Simon Leung gg / CC BY-SA 4.0 (cropped)
- Chemistry That Surpasses Living Organisms: “Chemicals in flasks” Joe Sullivan / CC BY 2.0 (cropped)
- Chemistry That Artificially Reproduces Life Phenomena: “P04971 homology model thrombin-like enzyme batroxobin” Fvasconcellos (talk · contribs) / Public domain (cropped)
- Synthesis of Polymers with Controlled Structures: “Plastic pellets” SuSanA Secretariat / CC BY 2.0 (cropped)
- Polymer Synthesis Using Carbon Dioxide: “A container of liquid carbon dioxide” Whoisjohngalt / CC BY-SA 4.0 (cropped)
- Related lab (今堀研究室): “Chemical traffic light reaction (green)” Pnotporn / CC BY-SA 4.0 (cropped)
- Related lab (橋詰研究室): “Nacreous aragonite ("mother-of-pearl") 7” James St. John / CC BY 2.0 (cropped)
- Related lab (国村研究室): “Préparation d'échantillons pour l'analyse de la composition chimique de roches par fluorescence X (Ifremer )” Stephane Lesbats / CC BY 4.0 (cropped)
- Related lab (永田研究室): “PV Accelerator Pilot Line 2” Tasmanet / CC BY-SA 3.0 (cropped)
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