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Hashizume Lab
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The lab learns from biological mechanisms to create hybrid materials that combine organic and inorganic components.
AboutAbout the lab
Hybridizing organic and inorganic materials
The Hashizume Lab studies the development of hybrid materials that combine organic and inorganic substances, as well as functional molecules.
Bone, for example, is also a hybrid in which collagen (organic) and apatite (inorganic) are composited at the nanoscale.
The lab seeks to understand the principles of biomineralization, the process by which living organisms form inorganic crystals, and uses them as an environmentally friendly way to fabricate hybrid materials.
The lab also incorporates wet processes such as the sol-gel method, and takes on the challenge of hybridizing combinations of materials that were previously impossible.
Key terms
- Biomineralization
- The process by which living organisms form inorganic crystals. The lab uses its principles to fabricate materials
- Apatite
- The inorganic component of bone. Bone is a hybrid in which collagen (organic) and apatite are composited at the nanoscale
- Sol-gel method
- A wet-process technique that uses a solution of metal alkoxides to composite materials with inorganic substances
ResearchResearch themes
The lab develops hybrid materials and functional molecules composed of organic and inorganic substances, based on material design at the nanoscale, and works on applications such as biomedical materials. Each student has a different research topic and carries out everything on their own, from designing and fabricating the target material to evaluating its structure and properties, and then writes up the results.
*Illustrative imageMaterials development using biological mechanisms
Apatite is deposited on the surfaces of various materials from aqueous solutions that mimic the inorganic ion environment of living organisms. Focusing on organic substances such as polysaccharides and proteins that serve as scaffolds, the lab investigates methods of compositing, control of apatite morphology, and potential as biomedical materials.
*Illustrative imageSurface modification of polymers
Using wet processes such as the sol-gel method, the lab composites the surfaces of various polymers with inorganic substances. The aim is to give only the outermost surface new properties while preserving the properties of the bulk, and to achieve strong bonding with inorganic substances. The approach is also applied to adhesion between dissimilar materials.
Materials from natural polysaccharides
The lab develops methods to hybridize polysaccharides, an abundant natural resource, and process them into films and fibers. It has found that the properties of films change with fabrication conditions even when the raw material is the same, and is also working on making films with properties suited to specific uses.
*Illustrative imageCatalysts that convert biomass into chemicals
The lab develops catalytic reactions that convert monosaccharides, obtained by hydrolyzing polysaccharides such as cellulose and chitin, into useful chemicals such as pharmaceuticals and polymer precursors. It is also developing composite catalysts that combine different catalysts.
MembersFaculty
- ProfessorMineo Hashizume
- LecturerTakuya Sagawa
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Nacreous aragonite ("mother-of-pearl") 7” James St. John / CC BY 2.0 (cropped)
- Materials development using biological mechanisms: “Biomimetic Morphology of Phyllotaxy Towers” Saleh Masoumi / CC BY-SA 3.0 (cropped)
- Surface modification of polymers: “Milled Polymer Surface 10х” Aiym Maksatkyzy / CC BY-SA 4.0 (cropped)
- Catalysts that convert biomass into chemicals: “Glass Pressure Reactor” Rudyher27 / CC BY-SA 4.0 (cropped)
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