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Itoh Lab
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A lab that takes on biological phenomena by decoding massive genome sequences through computational analysis.
AboutAbout the lab
Decoding large-scale genomes with computational analysis.
The Itoh Lab conducts bioinformatics research, decoding large-scale genome sequence data through computational analysis.
Its targets are massive amounts of genome and RNA sequence data, typified by data from next-generation sequencers.
By applying a variety of computational analysis techniques, the lab takes on the challenge of elucidating biological phenomena.
It also develops new computational methods for determining genome sequences accurately.
Key terms
- Bioinformatics
- A research field that analyzes biological data with computers to study the mechanisms of life
- Next-generation sequencer
- A device that reads the base sequences of DNA or RNA in massive quantities at once
- Genome
- The complete set of genetic information of an organism
ResearchResearch themes
The lab applies a variety of computational analysis techniques to large-scale genome and RNA sequence data, typified by data from next-generation sequencers, in order to elucidate biological phenomena. It also develops the computational methods themselves for assembling sequences correctly.
*Illustrative imageDecoding the Genomes of Living Organisms
The lab assembles the massive numbers of sequences read by next-generation sequencers to reconstruct the complete genomes of organisms. From sequence data, it explores biological questions such as the mechanism of sex determination in hops, the wasabi genome, and the evolution of ants and fish in Lake Victoria.
*Illustrative imageIntroducing Mutations into Organelle Genomes
To study how the small genomes of chloroplasts and mitochondria function, the lab is developing a technique for introducing random mutations only into those genomes. Using artificial fusion proteins, it aims to make it possible to investigate the relationship between mutations and traits.
MembersFaculty
- ProfessorTakehiko ItohPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “CSIRO ScienceImage 11313 The CSIRO GPU cluster at the data centre” division, CSIRO / CC BY 3.0 (cropped)
- Decoding the Genomes of Living Organisms: “Hop (Humulus lupulus) ( )” Luc.T from Buggenhout, België / CC BY 2.0 (cropped)
- Introducing Mutations into Organelle Genomes: “Clorofila 3” Wilfredor / CC0 (cropped)
- Related lab (山田研究室): “E coli at 10000x, original” Photo by Eric Erbe, digital colorization by Christopher Pooley, both of USDA, ARS, EMU. / Public domain (cropped)
- Related lab (佐藤研究室): “Aminoacyl-tRNA synthetase in complex with cognate tRNA” Oleksandr V. Savytskyi, Yaroslav V. Katrich / CC BY 4.0 (cropped)
- Related lab (藤研究室): “Xenopus laevis nucleosome, Histone H3.3C (2) 1AOI” Luger K, Mäder AW, Richmond RK, Sargent DF, Richmond TJ / CC0 (cropped)
- Related lab (梶川研究室): “Reverse transcriptase 1KLF” Thomas Splettstoesser (www.scistyle.com) / CC BY-SA 3.0 (cropped)
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