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Tagawa Lab
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The lab aims to create living organisms by reproducing tissues made of multiple cell types outside the body.

AboutAbout the lab
From cells to tissues, creating living organisms.
The Tagawa Lab studies how to reproduce, outside the body, tissues made of multiple types of cells.
Cell biology to date has cultured a single type of cell and used it for research.
This lab aims to go further and turn assemblies of interconnected tissues into a single living system.
It builds culture models of the liver and intestine as devices, and works on drug metabolism and on creating disease models of intestinal inflammation and viral infection.
Key terms
- Gut microbiota
- The community of bacteria living in the intestines of humans and animals. Besides digestion, it is also involved in breaking down drugs
- Drug metabolism
- The process by which a drug that enters the body is converted into other substances by enzymes in the liver and elsewhere
- Disease model
- A system that reproduces in cells or animals what happens in the body during a disease. It is used to evaluate drugs
NewsLab news
Master's and doctoral students win poster awards at an international symposium
A doctoral student wins an award for an oral presentation at an international conference on molecular medicine
An undergraduate student wins an award at the graduation thesis presentation
ResearchResearch themes
The lab aims to reproduce tissues composed of multiple cell types outside the body, and to turn assemblies of interconnected tissues into a living system. Under the banner of 'constructing a minimal mammalian system,' it works on culture models centered on the liver and intestine.
*Illustrative imageCulture model of liver tissue
The lab builds devices for culturing liver tissue outside the body and uses them as models for studying drug metabolism and how drugs move through the body.
*Illustrative imageCulture model of gut microbiota and the intestine
The lab builds devices that culture gut microbiota and intestinal tissue together, and likewise uses them as models for studying drug metabolism and how drugs move through the body.
*Illustrative imageIntestinal inflammation model
The lab is working to reproduce inflammation that occurs in the intestine on a cultured model.
*Illustrative imageViral infection model
The lab is working to build models that reproduce how viruses infect cultured tissue.
MembersFaculty
The members of the Tagawa Lab consist of faculty, researchers, postdoctoral researchers, doctoral, master's, and undergraduate students, research students, and secretaries.As of 2026
- Associate ProfessorYoh-Ichi TagawaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “96 well plate” J.N. Eskra / CC BY-SA 4.0 (cropped)
- Culture model of liver tissue: “72hr sodyum48 saat” Tolgaaslan / Public domain (cropped)
- Culture model of gut microbiota and the intestine: “E. coli Bacteria ( )” NIAID / Public domain (cropped)
- Intestinal inflammation model: “Organoid (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Viral infection model: “AAVs by electron microscopy” Graham Beards / CC BY-SA 4.0 (cropped)
- Related lab (粂・
白木研究室): “Human induced pluripotent stem cell colony ( )” NIH Image Gallery from Bethesda, Maryland, USA / Public domain (cropped) - Related lab (松浦研究室): “Phosphatidylcholine liposomes at phase-contrast microscopy” ArkhipovSergey / CC BY-SA 4.0 (cropped)
- Related lab (佐藤研究室): “Aminoacyl-tRNA synthetase in complex with cognate tRNA” Oleksandr V. Savytskyi, Yaroslav V. Katrich / CC BY 4.0 (cropped)
- Related lab (駒田・福嶋研究室): “Ubiquitin cartoon” en:User:Rogerdodd / Public domain (cropped)
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