LAB LOGA page on LabLog, a review site (not the lab's official page)
Kimura Lab
Machine-translated · View original
This lab studies the mechanisms that determine how genes function inside living cells.
AboutAbout the lab
Epigenetics inside living cells.
Kimura Lab studies why cells that carry the same genetic information take on different forms and functions.
The key is chemical modification of histones, the proteins that DNA wraps around.
These modifications change how genes function and are passed on through cell division. This phenomenon is called epigenetics.
The lab develops methods to observe histone modifications and transcription in living cells and organisms, and investigates their significance and regulatory mechanisms.
Key terms
- Epigenetics
- A phenomenon in which the way genes function changes and is inherited without any change in the DNA base sequence
- Histone
- A protein that DNA wraps around and packs onto. It serves as the foundation for housing DNA in the cell nucleus
- Transcription
- The process of making RNA using DNA as a template. It is the first step in the use of a gene
NewsLab news
View More ↗ResearchResearch themes
In multicellular organisms such as humans, almost every cell carries essentially the same DNA, yet different genes are active in different cells. Epigenetic regulation plays an important role in this control, through DNA methylation and through post-translational modifications of histones, the proteins that bind tightly to DNA.
*Illustrative imageLive-Cell Imaging of Histone Modifications
The lab developed a method for tracking the behavior of modified histones and phosphorylated RNA polymerase II inside living cells by introducing fluorescently labeled antibodies into the cells. The method is called FabLEM.
*Illustrative imageSignificance and Regulation of Histone Modifications
The lab produces monoclonal antibodies that distinguish various histone modifications, and examines how these modifications change during development, differentiation, and the cell cycle, and in response to external stimuli. It also works on developing methods to analyze the distribution of modifications from small numbers of cells.
MembersFaculty
Kimura Lab members include faculty, postdoctoral researchers, doctoral, master's, and undergraduate students, and administrative and technical assistants.As of 2025
- ProfessorHiroshi KimuraPublications ↗
- Assistant ProfessorSatoru IdePublications ↗
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Kimura Lab
To LabSchool of Life Science and Technology, Department of Life Science and TechnologyEpigenetics, plants, molecular genetics, and epigenome editi…
Kajikawa LabSchool of Life Science and Technology, Department of Life Science and TechnologyTransposable elements, retrotransposons, genome evolution, e…
Kamiya LabSchool of Life Science and Technology, Department of Life Science and TechnologyFluorescent probes, Raman probes, bioimaging
Kitaguchi LabSchool of Life Science and Technology, Department of Life Science and TechnologyBioimaging, biosensors, fluorescent proteins, antibodiesThe information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Nucleosome at enhancer with H3K122 acetylated” MethylC5 / CC0 (cropped)
- Live-Cell Imaging of Histone Modifications: “Mitotic LLC-PK1 cells, fluorescence microscopy ( )” ZEISS Microscopy from Germany / CC BY 2.0 (cropped)
- Significance and Regulation of Histone Modifications: “Structure of the intact human IgG B12 antibody (PDB 1hzh)” Elisa Fadda / CC BY 4.0 (cropped)
- Related lab (藤研究室): “Xenopus laevis nucleosome, Histone H3.3C (2) 1AOI” Luger K, Mäder AW, Richmond RK, Sargent DF, Richmond TJ / CC0 (cropped)
- Related lab (梶川研究室): “Reverse transcriptase 1KLF” Thomas Splettstoesser (www.scistyle.com) / CC BY-SA 3.0 (cropped)
- Related lab (神谷研究室): “Fluorescence rainbow” Maxim Bilovitskiy / CC BY-SA 4.0 (cropped)
- Related lab (北口研究室): “Crystal Jelly ("Aequorea Victoria"), Monterey Bay Aquarium, Monterey, California, USA” Jim G from Silicon Valley, CA, USA / CC BY 2.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.