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Shogo Hamada Lab
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The lab creates "living" molecular robots and materials from biomolecules.
AboutAbout the lab
Creating systems that make full use of biomolecules.
The Shogo Hamada Lab studies how to combine biomolecules such as DNA to build new systems.
The lab designs "molecular robots," which are not living organisms but have the characteristics of life, starting from the molecular level.
It is extending the technologies developed there to functional materials that can "think" and to diagnostic devices that test nucleic acids on the spot.
This is a new research area that emerged from the convergence of various fields, including information science, control engineering, chemistry, and biophysics.
Key terms
- Molecular robot
- An extremely small mechanism built by combining molecules, capable of moving and making decisions
- DNA origami
- A technology that folds long DNA to build nanostructures in any desired shape
- Artificial metabolic system
- A molecular mechanism that mimics the metabolism of living things so that it keeps taking in and transforming substances
NewsLab news
Results on the dynamic formation of DNA network materials were published in Small
A paper on the rational design of DNA gels was published in ACS Synth. Biol.
A student received the Young Researcher Encouragement Award at the Molecular Robotics Annual Meeting
Students received awards at BB2025 and the Cybownics Study Group
The lab's research was featured in the special issue "Advances in Molecular Robotics Technology" of the Journal of the Institute of Electronics, Information and Communication Engineers
ResearchResearch themes
The lab aims to create systems that are not living organisms but have the characteristics of life, starting from the molecular level. Building on design technologies for biomolecules, including DNA, it extends its research from molecular robots to materials and to medical testing and diagnostics.
*Illustrative image"Living" Molecular Robots
Based on an "artificial metabolic system" that mimics metabolism, which is essential to life, the lab implements characteristics unique to living things. It is developing molecular robots that move, think, regenerate and maintain themselves, and eventually evolve.
*Illustrative imageProgrammable Biomolecular Materials
DNA has the characteristic that information and matter are two sides of the same coin. Making use of this, the lab develops hybrid materials endowed with dynamic, programmable properties and functions.
*Illustrative imageDNA Nanosystems and Nanostructures
Using technologies such as its original DNA branched structures and DNA origami, the lab develops nanoscale devices and systems, as well as software for designing them. These are foundational technologies for molecular robots and material systems.
*Illustrative imageApplications to Medical Testing and Diagnostics
The lab applies the technologies developed in molecular robotics. It has launched a startup company that develops diagnostic devices that test nucleic acids on the spot, and is active through it.
MembersFaculty
The members of the Shogo Hamada Lab consist of faculty, technical staff, administrative staff, and doctoral, master's, and undergraduate students.As of 2026
- Assistant ProfessorShogo Shogo HamadaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “20251019 Replica DNA double helix model Berlin 03” Flocci Nivis / CC BY 4.0 (cropped)
- "Living" Molecular Robots: “DNA Origami Triangular” Matthias A. Fenner / CC BY-SA 4.0 (cropped)
- Programmable Biomolecular Materials: “Superabsorber Hydrogel KSG 2917 pK” Petra Klawikowski / CC BY-SA 3.0 (cropped)
- DNA Nanosystems and Nanostructures: “DNA Origami Triangular” Matthias A. Fenner / CC BY-SA 4.0 (cropped)
- Applications to Medical Testing and Diagnostics: “Microfluidic chip for point-of-care medical devices” FMNLab / CC BY 4.0 (cropped)
- Related lab (金崎研究室): “Atlas frontview 2013” DARPA / Public domain (cropped)
- Related lab (大上研究室): “Protein Crystal Structure of the human Sec23a-24a heterodimer, complexed with the SNARE protein Sec22b PDB 2nup” Emw / CC BY-SA 3.0 (cropped)
- Related lab (瀧ノ上正浩研究室): “2T7A4” Yma3591 / CC BY 4.0 (cropped)
- Related lab (齋藤研究室): “Utah teapot surreal” Dhatfield / CC BY-SA 3.0 (cropped)
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