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Applied Genetic Resources Lab
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The lab uses genomes to uncover how the components of medicinal plants are produced.
AboutAbout the lab
For the sustainable use of plant resources
The Applied Genetic Resources Lab studies, at the molecular level, how plants produce a wide variety of compounds.
The lab believes that the importance of plants as a source of pharmaceuticals lies in the diversity of the compounds they produce, that is, their chemical diversity.
The lab grew out of a pharmacognosy laboratory, and now studies plants, the raw materials of crude drugs, as living organisms.
The lab aims to apply its findings to the sustainable use of plant resources in the future.
Key terms
- Chemical diversity
- The great diversity in the types and structures of compounds that organisms produce
- Genome
- The entire set of genetic information an organism has, written as the sequence of DNA bases
- Metabolome
- The entire set of small molecules (metabolites) produced by metabolism in cells or tissues
NewsLab news
A master's student received the Outstanding Student Presentation Award at the 43rd Annual Meeting of the Japanese Society for Plant Biotechnology
A paper on integrated omics analysis of aconite (Aconitum) received the Paper Award of the Japanese Society of Pharmacognosy
A student received the Hitoshi Matsuo Award at the 61st Symposium on Phytochemistry
A paper on tissue culture and component analysis of Uncaria rhynchophylla published in Plant Biotechnology
A paper on multi-omics analysis of aconite published in J. Natural Medicines
ResearchResearch themes
The lab uncovers how plants produce substances at the molecular level, clarifying the molecular basis of their chemical diversity. Using the genome as a clue, it investigates how plants produce such a wide variety of compounds.
*Illustrative imagePlant metabolite production and chemical diversity
Plants make large amounts of organic compounds from carbon dioxide through photosynthesis, and these compounds are extremely diverse. The lab elucidates the mechanisms of this production at the molecular level, and clarifies the molecular basis of the chemical diversity of plants as a source of pharmaceuticals.
*Illustrative imageReading metabolite production from genomic information
The complex mechanisms of living organisms can be investigated using the genetic information in the genome. In addition to the genome, the lab integrates and analyzes the transcriptome, proteome, and metabolome layers to capture the whole picture of how plants produce substances.
MembersFaculty
The members of the Applied Genetic Resources Lab consist of faculty and doctoral, master's, and undergraduate students.As of 2026
- ProfessorMami Yamazaki
- Associate ProfessorNaoko Yoshimoto
- Assistant ProfessorRyosuke Sugiyama
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Benjamin Rush Medicinal Plant Garden - IMG 7240” Daderot / Public domain (cropped)
- Plant metabolite production and chemical diversity: “Fresh Green Peperomia Pellucida Sirih Cina Leaves Macro Nature Background” Undeka 11 / CC BY-SA 4.0 (cropped)
- Reading metabolite production from genomic information: “Illumina NextSeq 500” Konrad Förstner / CC BY 2.0 (cropped)
- Related lab (天然物創薬化学): “Picture from an organic chemistry laboratory” Sil.d / CC BY 4.0 (cropped)
- Related lab (予防薬学): “HR-ICP-MS, high-resolution inductively coupled plasma ionization mass spectrometer used for multi-element analysis, in CAFIA laboratory, Czech Republic” Sarka Na kopci / CC BY-SA 4.0 (cropped)
- Related lab (生物薬剤学): “Atenolol tablets (UK)” Whispyhistory / CC BY-SA 4.0 (cropped)
- Related lab (薬品合成化学): “Molecular model of the pre-pore form of a MACPF protein based upon the structure of pneunolysin” Jcwhizz at English Wikipedia / CC BY-SA 3.0 (cropped)
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