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Microbial Engineering Lab
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The lab explores how microorganisms that can live without oxygen function, and applies this to fermentation and the environment.

AboutAbout the lab
Exploring the way of life of microbes that do not need oxygen.
The Microbial Engineering Lab studies microorganisms discovered in the environment, as well as lactic acid bacteria and yeasts.
Its particular strength is research on anaerobic microorganisms, which do not need oxygen to grow.
The lab covers both basic research, which examines the functions of proteins and genes, and applied research related to fermented foods and alcoholic beverages, purification of contaminated soil, and organic farming.
Key terms
- Anaerobic microorganisms
- Microorganisms that do not need oxygen to grow. Some cannot grow when oxygen is present
- Anaerobic respiration
- A form of respiration that obtains energy by using substances other than oxygen, such as nitrate or iron
- Continuous cropping obstacle
- Poor plant growth, caused by disease and other problems, when the same crop is grown repeatedly in the same field
ResearchResearch themes
The lab collects, isolates, and identifies new microorganisms relevant to environmental problems and the food industry, and studies them with a wide range of techniques, including analysis of genomes, genes, and proteins. It aims to carry out original basic and applied research on how microorganisms live.
*Illustrative imageBacteria that "breathe" iodine and arsenic
Certain bacteria respire substances other than oxygen. The lab isolates bacteria that respire iodine, arsenic, antimony, and vanadium, which have rarely been studied, and seeks to clarify how their anaerobic respiration works.
*Illustrative imageThe key enzyme in anaerobic respiration
The lab analyzes the molybdenum–iron-sulfur protein complex (MopB), a key enzyme in bacterial anaerobic respiration, from biochemical and structural perspectives, with the aim of understanding the mechanism of anaerobic respiration.
*Illustrative imageMicroorganisms in rum making
In joint research with a private company in Chiba Prefecture, the lab uses culturing and next-generation sequencers to study the activity of the lactic acid bacteria, acetic acid bacteria, and yeasts that become dominant during rum fermentation. It also contributes to new product development by selecting yeasts that produce a pleasant aroma.
*Illustrative imageDisinfecting soil with the power of microorganisms
The lab has isolated anaerobic microorganisms that become dominant during reductive soil disinfestation, an environmentally friendly method for preventing continuous cropping obstacles. It is testing whether applying the volatile fatty acids produced by these bacteria directly to soil can provide cheaper and more stable disinfection.
MembersFaculty
The members of the Microbial Engineering Lab consist of faculty and doctoral, master's, and undergraduate students.
- ProfessorSeigo Amachi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Microbiology practical” M Joko Apriyo Putro / CC BY-SA 4.0 (cropped)
- Bacteria that "breathe" iodine and arsenic: “Colonie batteriche o vita marina?” Chiara.marraccini / CC BY-SA 4.0 (cropped)
- The key enzyme in anaerobic respiration: “Crystal structure of Tryptophan-7-Halogenase” Jmont31 / CC BY-SA 4.0 (cropped)
- Microorganisms in rum making: “Guadeloupe rhum fermentation tanks” Stefan Ivanovich / CC BY-SA 3.0 (cropped)
- Disinfecting soil with the power of microorganisms: “Field soil sampling” Prof. Dr. Alessandro Samuel-rosa / CC0 (cropped)
- Related lab (Bioresource Chemistry Lab): “PerkinElmerICP-768x576” 作者不詳 / Public domain (cropped)
- Related lab (Molecular Biofunction Lab): “Plant Cells, Being Plasmolyzed” Ouotro / CC BY 4.0 (cropped)
- Related lab (Biomolecular Chemistry Lab): “Molecule display ( )” allispossible.org.uk / CC BY 2.0 (cropped)
- Related lab (Molecular Biofunction Lab (Hanaoka Group)): “Clorofila 3” Wilfredor / CC0 (cropped)
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