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Evolutionary Genetics Lab
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An evolutionary genetics lab that uses Drosophila to explore how species diverge.

AboutAbout the lab
Exploring how species diverge, using Drosophila.
The Evolutionary Genetics Lab uses Drosophila (fruit flies) to study the genetic mechanisms of speciation, the process by which new species arise.
Hybrids between different species are rarely seen in nature, and most of them are sterile and cannot leave offspring.
The lab believes that species persist because reproductive isolation keeps them from mixing, and that new species arise when such isolation is acquired.
On the lab's website, it is introduced under the name "Evolutionary Genetics Laboratory (Kyoichi Sawamura Lab)."
Key terms
- Speciation
- The emergence of a new species when reproductive isolation arises between populations of organisms. It is considered a driving force of evolution.
- Reproductive isolation
- A mechanism that keeps different species from fusing genetically even if they mate, so that each persists as a species.
- Postzygotic isolation
- A mechanism in which mating is possible but the resulting hybrids die or are sterile, so the species do not mix.
ResearchResearch themes
Different species can persist without mixing with one another because of reproductive isolation. Aiming to elucidate its genetic mechanisms, the lab conducts research using Drosophila. The content of the research page dates from around 2017.
*Illustrative imagePostzygotic isolation: hybrid lethality and sterility
In crosses between Drosophila melanogaster and its close relatives, depending on the combination of parental sexes, either the hybrid males or the hybrid females die, and the surviving sex is sterile. From research on genes that rescue lethality and sterility, the lab has proposed a general model in which the cause may be the coevolution of heterochromatin and its binding proteins.
*Illustrative imagePremating isolation: courtship song and chromosomes
Drosophila ananassae and Drosophila pallidosa differ in the pattern of the male courtship song, and interspecific mating rarely takes place. The lab examines which males females of a strain with mixed genomes of both species accept, and is identifying the chromosomal regions involved.
MembersFaculty
The lab's members consist of faculty and master's students.As of 2019
- Associate ProfessorKyoichi Sawamura
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Spotted Wing fruit flies enjoy a banana ( )” Martin Cooper from Ipswich, UK / CC BY 2.0 (cropped)
- Postzygotic isolation: hybrid lethality and sterility: “Culture vials of Drosophila melanogaster in Unifei” Mateus S. Figueiredo / CC BY 4.0 (cropped)
- Premating isolation: courtship song and chromosomes: “Polyten chromosome” LPLT / Public domain (cropped)
- Related lab (Niwa Lab): “Fruit fly (Diptera, Tephritidae) ( )” Insects Unlocked / CC0 (cropped)
- Related lab (Evolutionary Genomics (Daiki Sato) Lab): “Italian honeybee brood frame from Langstroth hive” Benlisquare / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Phylogenetics Lab): “Darwin tree” Charles Darwin / Public domain (cropped)
- Related lab (Molecular Genetics Lab): “Dictyostelium discoideum 06” Usman Bashir / CC BY-SA 4.0 (cropped)
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