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Health Informatics Lab
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The lab investigates the pathophysiology of multifactorial diseases such as lifestyle-related diseases, kidney disease, liver cancer, and psychiatric disorders.
AboutAbout the lab
Analyzing the causes and pathophysiology of multifactorial diseases.
The Health Informatics Lab, part of the Department of Applied Information Sciences, studies lifestyle-related diseases, kidney disease, cardiovascular disease, chronic liver disease and liver cancer, and psychiatric disorders.
The faculty belong to the Health Administration Center of the Institute for Excellence in Higher Education, and Professor Suzuki is also listed as faculty in Pathophysiological Informatics at the Graduate School of Medicine.
Building on MA-5, a drug for mitochondrial disease, Professor Suzuki is developing treatments for kidney disease that make use of its action of increasing NAD+ and SIRT proteins.
From a psychiatric perspective, Assistant Professor Kita is examining the medical information about transgender people that appears in the media.
Key terms
- Health-related QOL
- The part of quality of life (QOL) that relates to health. Here, its relationship to prognosis is being examined
- Metabolome analysis
- A comprehensive, quantitative analysis of metabolites. The lab uses it to clarify the mechanisms of onset and the pathophysiology of lifestyle-related diseases
- MA-5
- A compound developed as a treatment for mitochondrial disease. It increases ATP in cells and reduces oxidative stress
ResearchResearch themes
Homeostasis in living organisms consists of regulatory systems such as neural, humoral, and behavioral ones. These respond to external and internal stresses over timescales from seconds to years and compensate for them, thereby maintaining vital functions. The lab analyzes the causes and pathophysiology of lifestyle-related diseases, kidney disease, cardiovascular disease, chronic liver disease and liver cancer, and psychiatric disorders.
*Illustrative imageLifestyle-related diseases and kidney disease
To clarify the mechanisms of onset and the pathophysiology of lifestyle-related diseases such as hypertension and diabetes, which accelerate kidney disease and arteriosclerosis, the lab investigates mitochondrial dysfunction and abnormalities of the gut microbiota through metabolome analysis and analysis of epigenetic changes. It conducts research aimed at clinical application jointly with the Division of Nephrology at the Graduate School of Medicine and the Division of Molecular Pathophysiology and Biomedical Engineering at the Graduate School of Biomedical Engineering.
*Illustrative imageEpidemiology of adult congenital heart disease
The lab examines the relationship between health-related QOL and prognosis in patients with congenital heart disease who have reached adulthood. It also works to clarify developmental disorders and aging-related risks through analysis of brain MRI images and other data.
*Illustrative imageChronic liver disease and liver cancer
In chronic liver diseases such as hepatitis B and fatty liver disease, the lab analyzes the mechanisms by which the disease progresses and searches for new treatments. It also analyzes factors associated with treatment outcomes and prognosis in liver cancer.
Psychiatric disorders and central histamine
The lab studies the role of central histamine in psychiatric disorders and searches for susceptibility genes for psychiatric disorders.
MembersFaculty
- ProfessorChihiro Ito
- ProfessorTakehiro Suzuki
- Associate ProfessorShunsuke Tatebe
- Associate ProfessorJun Inoue
- Assistant ProfessorHiroki Kita
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Blood pressure monitor” Adefanike / CC BY-SA 4.0 (cropped)
- Lifestyle-related diseases and kidney disease: “Ultrasound of left kidney renal parenchymal disease” Cerevisae / CC BY-SA 4.0 (cropped)
- Epidemiology of adult congenital heart disease: “Cardiovascular system - Congenital heart disease -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Chronic liver disease and liver cancer: “Ultrasound of upper right liver lobe showing fatty liver” Cerevisae / CC BY-SA 4.0 (cropped)
- Related lab (Biological Information Systems Science Lab): “Integrated Genome Browser 9.1.0 showing chromosome 1 of the human genome assembly hg38” Aloraine / CC BY-SA 4.0 (cropped)
- Related lab (Information and Communication Software Lab): “DHL Netherlands local site computer room server racks - IMG 3297” Jemimus / CC BY 2.0 (cropped)
- Related lab (Embodied Intelligence Robotics Lab): “Otonaroid® (adult android), a teleoperated android robot that lets you talk to other through an android, exhibited at Miraikan ( by Franklin Heijnen)” Franklin Heijnen / CC BY-SA 2.0 (cropped)
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