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生物化学
Showing the original Japanese · View translation
細胞が力や低酸素を感じて応答する仕組みを探る研究室。
AboutAbout the lab
細胞は力を感じて、形や動きを変える。
分子細胞生物分野
筋肉や骨は
細胞が
低酸素への
Key terms
- 力覚応答
- 細胞が
機械的な 力を 感じ取り、 細胞骨格を 作りかえて 対応する 反応。 メカノストレス応答とも 呼ばれる - 細胞骨格
- 細胞の
中に ある 構造。 細胞の 形や 運動に 関わり、 状況に 応じて 作りかえられる - Rho-GEF
- Rhoファミリーの
タンパク質を 活性化する 因子。 アクチン骨格の 作りかえの 制御に 関わる - BioID法
- 注目する
タンパク質と 相互作用する タンパク質に、 生きた 細胞内で ビオチンの 印を 付けて 見つける 方法 - 細胞競合
- 性質の
異なる 細胞どうしが 競合し、 片方が 排除される 現象
ResearchResearch themes
細胞は、
*Illustrative image細胞集団の秩序化とSolo
Rho-GEFの
*Illustrative imageRho-GEFと結合するタンパク質の探索
力を
*Illustrative imageメカノセンサーと情報伝達の解明
張力を
*Illustrative image細胞競合と力覚応答
上皮組織で
MembersFaculty
大橋研究室の
- Professor大橋 一正
- Associate Professor安元 研一
- Assistant Professor千葉 秀平
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The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Spinal cord gray matter immunofluorescence staining, confocal imaging” Wisstock / CC BY 4.0 (cropped)
- 細胞集団の
秩序化と Solo: “Limbal epithelial cells. Monolayer. SEM-BSE” Ivan A. Novikov / CC BY-SA 4.0 (cropped) - Rho-GEFと
結合する タンパク質の 探索: “Polyacrylamide gel electrophoresis of Proteins” Jean-Etienne Minh-Duy Poirrier from Bruxelles, Belgium / CC BY-SA 2.0 (cropped) - メカノセンサーと
情報伝達の 解明: “Actin Filaments in a Neuroblastoma cell Line” Howard Vindin / CC BY 4.0 (cropped) - 細胞競合と
力覚応答: “Salivary gland epithelial tissue growing in vitro” Irebustini / CC BY 4.0 (cropped) - Related lab (分析化学): “Fluorescence microscopy of the DNA of the oral cancer cells” Korinna / CC BY 4.0 (cropped)
- Related lab (理論化学): “Model 21-103 Mass Spectrometer in use at Exxon analytical research laboratory 1974” Courtesy of Science History Institute, No Known Copyright / Public domain (cropped)
- Related lab (量子化学): “Studying water” Pawel Nowakowski / CC BY-SA 4.0 (cropped)
- Related lab (有機化学第一): “In the Lab for Chemistry of Plant Polymers” Yulia Kolosova / CC BY 4.0 (cropped)
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