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Pharmacology Lab
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The lab studies pharmacology, using drugs to explore how glial cells in the brain function.
AboutAbout the lab
Using drugs to uncover how the body works
The Pharmacology Lab studies how drugs and chemical substances act on the body.
Using drug effects as a clue, the lab investigates the functions of excitable cells such as nerve and muscle cells.
Recently, the lab has focused on glial cells in the brain, examining the transmitters they release and the mechanisms inside these cells.
The lab is recruiting graduate students and also accepts collaborative research.
Key terms
- Astrocyte
- A type of glial cell found in the brain and spinal cord. It supports the function of neurons and the regulation of blood vessels
- Gliotransmitter
- Substances released from glial cells that regulate how neural signals are transmitted and inflammation. Examples include ATP and adenosine
- Adrenergic receptor
- Cell receptors that receive noradrenaline and similar substances. They are also a target of sedatives
NewsLab news
Paper by Assistant Professor Eguchi accepted for publication in Purinergic Signalling
Paper by Assistant Professor Eguchi accepted for publication in In Vitro Cellular & Developmental Biology - Animal
A doctoral student won the Excellent Presentation Award at the Young Researchers' Meeting on Neurobehavioral Pharmacology
A doctoral student won the top Enrei Award at the Akai Ito Kai meeting at Hokkaido University
A student won an Excellence Award at the Japanese Society for Neurochemistry Photo Contest
ResearchResearch themes
The lab investigates how drugs and chemical substances act on the body, using nerve, muscle, and secretory tissues as well as cells, with the aim of clarifying how the body works. Recently, it has focused on astrocytes, a type of glial cell in the brain.
*Illustrative imageHow gliotransmitters are produced and what they do
Using cultured astrocytes, the lab examines how gliotransmitters such as ATP and adenosine are released and metabolized. It also analyzes the relationship between behavior and changes in purine release and metabolism in the brain, using depression model mice.
*Illustrative imageRegulation of astrocyte process morphology
The lab studies how the shape of astrocyte processes changes through adrenergic receptors, which are also a target of sedatives. By combining in vivo, tissue, and cultured cell experiments, it aims to clarify how process morphology relates to brain function.
MembersFaculty
The members of the Pharmacology Lab are faculty and doctoral and undergraduate students.As of 2026
- ProfessorKenichi Otsuguro
- Assistant ProfessorRyota Eguchi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Human astrocyte” Bruno Pascal / CC BY-SA 3.0 (cropped)
- How gliotransmitters are produced and what they do: “Without AraC ICH 9 DIV Neuroastroglial culture” Ivan Tarzhanov / CC BY 4.0 (cropped)
- Regulation of astrocyte process morphology: “NG-2 progenitors and astrocytes in culture” Oleg Tsupykov / CC BY-SA 4.0 (cropped)
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