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分子シグナル制御分野
Showing the original Japanese · View translation
細胞の中の情報伝達のしくみを分子レベルで解き明かし、病気の診断や治療につなげる研究室。

AboutAbout the lab
細胞の情報伝達を、病気の克服へ。
分
特に、
がんや
Key terms
- シグナル伝達
- 細胞の
外や 中で 受けた 刺激を、 分子から 分子へと 順に 伝えて、 細胞の 反応を 引き起こすしく み - MAPキナーゼ・カスケード
- 3種類の
リン酸化酵素 (キナーゼ)が 順には たらき、 細胞の 増殖や死を 決める 信号を 伝える 経路 - ストレス顆粒
- ストレスを
受けた 細胞の 中に 一時的に できる、 mRNAやタンパク質の 集まり - アポトーシス
- 不要に
なった 細胞や 傷ついた 細胞が、 自ら 決まった 手順で 死ぬ しく み
NewsLab news
環境の
変化の 中で 生命が 恒常性を 保つしく みの 論文が Nature Communications 誌に 掲載 学生が、
第48回 日本分 子生物学会年会で 優秀ポスター賞を 受賞 学生が、
第19回日本臨床ストレス応答学会大会で 優秀発表賞を 受賞 学生が、
第84回日本癌学会学術総会で 優秀ポスター賞を 受賞 癌遺伝子産物に
対する 生体応答と 新たな 癌抑制機構の 論文が 掲載
ResearchResearch themes
細胞の
*Illustrative imageストレスに応じるMAPKKK、MTK1
ストレスに
*Illustrative imageストレス応答経路を止めるしくみと発癌
ストレス応答経路の
*Illustrative imageシグナルを混線させないしくみ
ERK・p38・JNKの
*Illustrative imageストレス顆粒と細胞死・抗癌剤への抵抗性
ストレス顆粒が
MembersFaculty
分
- Professor武川 睦寛Publications ↗
- Lecturer久保田 裕二Publications ↗
- Assistant Professor平沼 亮佑
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “MAPK-pathway-mammalian” Bubus12 / CC BY-SA 3.0 (cropped)
- ストレスに
応じる MAPKKK、 MTK1: “Kinase function” Aarya Venkat / CC BY-SA 4.0 (cropped) - ストレス応答経路を
止める しくみと 発癌: “General phosphatase mechanism” Lovinne / CC BY-SA 4.0 (cropped) - シグナルを
混線させないしく み: “MAPK cascade” OBRI Masters / CC BY 4.0 (cropped) - ストレス顆粒と
細胞死・抗癌剤への 抵抗性: “Immunofluorescence showing P-bodies and nucleus” Turiya1952 / CC BY-SA 4.0 (cropped)
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