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Veterinary Internal Medicine Lab
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A lab that uncovers internal medicine diseases of dogs and cats at the genomic level and translates the findings into treatment.
AboutAbout the lab
Turning “incurable diseases” into “curable diseases.”
The Veterinary Internal Medicine Lab pursues the questions “Why do animal diseases occur?” and “How can they be cured?”
The lab is in charge of the internal medicine services at the University of Tokyo Animal Medical Center, where it studies problems arising in clinical practice and links the findings to treatment.
Focusing on blood diseases, tumors, and gastrointestinal diseases in dogs and cats, the lab incorporates genome analysis technologies to uncover new disease conditions.
Because dogs and cats live in environments close to humans and share many similar diseases, this research also brings new insights to human medicine.
Key terms
- Lymphoma
- A cancer of lymphocytes, a type of immune cell. It is the most common blood cancer in animals.
- Next-generation sequencer
- A device that reads large amounts of DNA or RNA sequences quickly, making it possible to comprehensively search for genetic abnormalities.
- Biomarker
- A substance found in blood and other samples that serves as an indicator of whether a disease is present and how far it has progressed.
NewsLab news
A doctoral student completed the program after receiving the Dean’s Award of the Graduate School
A doctoral student received a Research Award at the Annual Meeting of the Japan Academy of Veterinary Internal Medicine
A student received an Outstanding Presentation Award from the Clinical Division of the Japanese Society of Veterinary Science
ResearchResearch themes
While treating internal medicine diseases of dogs and cats at the affiliated Animal Medical Center, the lab aims to elucidate disease mechanisms and establish new diagnostic and treatment methods. Research is carried out in hematology, oncology, cardiology, gastroenterology, and infectious diseases, with genome analysis technologies actively adopted.
*Illustrative imageMechanisms and Treatment of Bone Marrow Diseases
The lab found that bone marrow diseases that cause conditions such as anemia are common in Miniature Dachshunds. By examining genetic abnormalities with next-generation sequencing, it aims to develop treatments that are effective for cases that are difficult to treat.
*Illustrative imageResearch on Lymphoma and Histiocytic Sarcoma
The lab investigates the genetic abnormalities of canine histiocytic sarcoma, which is difficult to cure, the mechanisms by which canine lymphoma becomes resistant to anticancer drugs, and the abnormalities of lymphoid cancers in cats, aiming to develop new treatments.
*Illustrative imageEffects of Anticancer Drugs on the Heart
Anticancer drugs can damage the heart and blood vessels. Using biomarkers, echocardiography, and mouse models, the lab investigates the mechanisms behind this damage, aiming to apply the findings to prevention and early detection.
*Illustrative imageIntestinal and Gallbladder Diseases in Dogs
For intestinal lymphangiectasia and gallbladder mucocele, which are common in dogs, the lab investigates how these diseases develop using tissue obtained by endoscopy and diagnostic imaging, aiming to develop new treatments and preventive methods.
MembersFaculty
The members of the Veterinary Internal Medicine Lab include faculty, project researchers, postdoctoral researchers, specially appointed support staff for agriculture, secretaries, and doctoral and undergraduate students.As of 2025
- ProfessorMasaru OkudaPublications ↗
- Associate ProfessorHirotaka TomiyasuPublications ↗
- Project Associate ProfessorYuko Goto-Koshino-Koshino
- Project Assistant ProfessorAki Ohmi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “1 Year Old Miniature Dachshund” Idk48 / CC0 (cropped)
- Mechanisms and Treatment of Bone Marrow Diseases: “Myeloblast with Auer rod smear” Paulo Henrique Orlandi Mourao / CC BY-SA 3.0 (cropped)
- Research on Lymphoma and Histiocytic Sarcoma: “Canine lymphoma 1” Joel Mills / CC BY-SA 3.0 (cropped)
- Effects of Anticancer Drugs on the Heart: “Dilated cardiomyopathy B-Mode” Kalumet / CC BY-SA 3.0 (cropped)
- Intestinal and Gallbladder Diseases in Dogs: “Atrophy of duodenal folds” DV Balaban, A Popp, F Vasilescu, D Haidautu, RM Purcarea, M Jinga / CC BY 4.0 (cropped)
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- Related lab (獣医臨床病理学): “Cat and Dog Cuddling” SeanT313 / CC BY-SA 4.0 (cropped)
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業動物臨床学研究室): “Row of Holstein Friesian cows in Bronów” Mikinisk / CC BY-SA 4.0 (cropped)
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