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Large Animal Clinical Medicine Lab
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The lab works with veterinarians in the field to uncover the causes of diseases in cattle and other production animals that are difficult to diagnose.

AboutAbout the lab
Uncovering diseases that are hard to diagnose in the field.
The Production Animal Clinical Medicine Lab is responsible for research, education, and clinical practice on diseases of cattle and other production animals.
On farms, large-scale diagnostic equipment is often hard to use, and it is not uncommon for a case to end without anyone knowing what the disease actually was.
The lab analyzes such difficult-to-diagnose cases in collaboration with veterinarians in the field and the Veterinary Pathology Lab, and returns the results of definitive diagnoses to the field.
Fieldwork is carried out mainly at the university's affiliated farm in Kasama, Ibaraki Prefecture, and the lab currently operates as a research group within the Veterinary Reproduction and Breeding Lab.
Key terms
- Enzootic bovine leukosis
- A disease in which a bovine leukemia virus infection causes cancer of the lymphocytes in cattle
- Definitive diagnosis
- Making the final determination of what disease an animal has by combining the results of tests
- Pathology
- The field of study that examines changes in organs and tissues, for example under a microscope, to clarify the causes and development of disease
ResearchResearch themes
The lab aims to analyze the pathology of cases that are difficult to diagnose in clinical practice for production animals, and to develop systematic diagnostic methods. Its central research topic is enzootic bovine leukosis, and it also works on blood, heart, nervous system, and hereditary diseases, parasites of sheep, and infectious diseases carried by ticks.
*Illustrative imageBlood Diseases of Cattle
The lab studies the mechanisms by which enzootic bovine leukosis, caused by a virus, develops, and methods for making a definitive diagnosis while the animal is still alive. It also aims to correctly diagnose rare blood diseases in production animals.
*Illustrative imageDiagnosis of Heart Diseases in Cattle
Cases that were difficult to diagnose are examined using heart sounds, electrocardiography, and echocardiography, and the data are accumulated together with definitive pathological diagnoses. The lab also aims to develop technology for automatically detecting heart murmurs.
*Illustrative imageDiagnosis of Neurological Diseases in Cattle
Because CT and MRI are difficult to use in production animal practice, the lab is systematizing the procedures for neurological examination to suit this setting. It is also searching for markers in blood and cerebrospinal fluid that can distinguish neurological diseases.
*Illustrative imageHereditary Diseases of Cattle
For new hereditary diseases in Holstein cattle discovered through genome analysis, the lab's task is to confirm the symptoms, mode of inheritance, and effects on production in clinical settings.
MembersFaculty
The members of the Production Animal Clinical Medicine Lab consist of faculty members, doctoral students, and undergraduate students.As of 2025
- ProfessorHisashi InokumaPublications ↗
- Project Assistant ProfessorMasaki MaezawaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Row of Holstein Friesian cows in Bronów” Mikinisk / CC BY-SA 4.0 (cropped)
- Blood Diseases of Cattle: “Cow blood sampling” Agungtrinugroho / CC BY-SA 4.0 (cropped)
- Diagnosis of Heart Diseases in Cattle: “Bovine heart” Museum of Veterinary Anatomy FMVZ USP / Wagner Souza e Silva / CC BY-SA 4.0 (cropped)
- Diagnosis of Neurological Diseases in Cattle: “Cerebellum Cross Section ( )” Berkshire Community College Bioscience Image Library / CC0 (cropped)
- Hereditary Diseases of Cattle: “HOLSTEIN FRIESIAN CALF” Ranjithkumar Murugesan / CC0 (cropped)
- Related lab (Veterinary Clinical Pathology Lab): “Cat and Dog Cuddling” SeanT313 / CC BY-SA 4.0 (cropped)
- Related lab (Veterinary Hygiene Lab): “Laboratory rat” Anna Marchenkova / CC BY 4.0 (cropped)
- Related lab (Veterinary Public Health Lab): “Black-mouse-trio-in-cage-2” Commissioned by Understanding Animal Research / CC BY-SA 4.0 (cropped)
- Related lab (Veterinary Internal Medicine Lab): “1 Year Old Miniature Dachshund” Idk48 / CC0 (cropped)
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