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Protein Engineering Lab (Jose Caaveiro)
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A lab that uses protein engineering and structural biology to develop new antibody- and vaccine-based therapeutics.
AboutAbout the lab
Developing new therapeutics with antibodies and vaccines
Prof. Caaveiro's lab specializes in protein engineering and structural biology, and researches the development of new therapeutics centered on antibodies and vaccines.
The lab aims to develop and improve treatments for infectious diseases, neurological diseases, endocrine and immune disorders, and cardiovascular diseases.
The professor belongs to the Faculty of Pharmaceutical Sciences and, in the School of Interdisciplinary Science and Innovation, teaches a Research Project course (Human and Life domain).
Key terms
- Structural biology
- A research field that investigates the three-dimensional shapes of molecules such as proteins in order to understand how they function.
- X-ray crystallography
- A method of crystallizing a protein, exposing it to X-rays, and determining the molecule's three-dimensional structure.
- Immunotoxin
- A molecule in which a toxin is attached to an antibody. Its preparation and optimization is one of the lab's research themes.
ResearchResearch themes
Prof. Caaveiro specializes in protein engineering and structural biology, and works on developing new therapeutics centered on antibodies and vaccines. The aim is to develop and improve treatments for infectious diseases, neurological diseases, endocrine and immune disorders, and cardiovascular diseases.
*Illustrative imageApplying AI to Antibody Research
A theme that applies artificial intelligence (AI) to antibody research. The listed research keywords include antibodies, fluctuations, CAR-T cells, structural biology, and molecular dynamics (MD) simulation.
*Illustrative imageNorovirus Vaccines
A theme dealing with norovirus vaccines. The professor's listed areas of expertise include developing new therapeutics centered on antibodies and vaccines.
*Illustrative imagePreparation and Optimization of Immunotoxins
A theme on preparing and optimizing immunotoxins. The researcher information lists "preparation and optimization of immunotoxins" as a research theme.
*Illustrative imageX-ray Crystallography of Proteins
A theme that investigates protein structures by X-ray crystallography. The researcher information lists "X-ray crystal structure" as a research keyword.
MembersFaculty
- ProfessorJose Caaveiro
VoicesStudent voices
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Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Protein Engineering Lab (Jose Caaveiro)
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “SHOC2 protein crystal structure” Achaparro0600 / CC BY-SA 4.0 (cropped)
- Applying AI to Antibody Research: “Protein composite” Thomas Splettstoesser (www.scistyle.com) / CC BY-SA 3.0 (cropped)
- Norovirus Vaccines: “Japanese female scientist wearing plastic gloves holding syringe and vial, researching a coronavirus vaccine ( )” Japanexperterna.se from Japan / CC BY 2.0 (cropped)
- Preparation and Optimization of Immunotoxins: “Comparison of the glycan shields of viral class I fusion proteins” Yasunori Watanabe, Zachary T. Berndsen, Jayna Raghwani, Gemma E. Seabright, Joel D. Allen, Oliver G. Pybus, Jason S. McLellan, Ian A. Wilson, Thomas A. Bowden, Andrew B. Ward & Max Crispin / CC BY-SA 4.0 (cropped)
- X-ray Crystallography of Proteins: “LOV2 domain of phototropin-2 protein from Arabidopsis thaliana” TBwichem / CC0 (cropped)
- Related lab (Protein Engineering Lab): “Smallpox vaccine” Photo Credit: James Gathany Content Providers(s): CDC / Public domain (cropped)
- Related lab (Mineralogy Lab): “Brown calcite crystals ( )” James Petts from London, England / CC BY-SA 2.0 (cropped)
- Related lab (Mineralogy Lab): “Gypsum - Sieroszowice mine, Lubin, Lower Silesia, Poland” Ivar Leidus / CC BY-SA 4.0 (cropped)
- Related lab (Muscle Cell Biology Lab): “Chick embryo 3d” PaulT (Gunther Tschuch) / CC BY-SA 4.0 (cropped)
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