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Protein Engineering Lab
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The lab explores new therapeutics, such as antibodies and vaccines, from a structural perspective.
AboutAbout the lab
Creating new therapeutics from antibodies and vaccines
Prof. Caaveiro's lab specializes in protein engineering and structural biology, and works on developing new therapeutics centered on antibodies and vaccines.
In a message to high school students, the professor writes that the lab aims to develop and improve therapeutic approaches for infectious diseases, neurological diseases, disorders of the endocrine and immune systems, and diseases of the heart and blood vessels.
The research themes listed in the researcher profile include a theme on using AI in antibody research and a norovirus vaccine.
In the Faculty of Collaborative Regional Innovation, the professor teaches pharmaceutical sciences classes within the Research Project course (Human and Life Sciences area), one of the project-based subjects.
Key terms
- Antibodies
- A protein that binds to a specific molecule. In this lab, it is at the center of research on therapeutics and vaccines
- Structural biology
- A field that investigates the three-dimensional structures of proteins and other molecules in order to understand how they function
- X-ray crystallography
- A method of determining a protein's three-dimensional structure from the arrangement of its atoms, by crystallizing the protein and exposing it to X-rays
ResearchResearch themes
The lab aims to develop and improve therapeutic approaches for infectious diseases, neurological diseases, disorders of the endocrine and immune systems, and diseases of the heart and blood vessels. The research themes in the researcher profile include AI, antibodies, vaccines, immunotoxins, and X-ray crystallography.
*Illustrative imageUsing AI in Antibody Research
This theme uses AI in antibody research. The research keywords listed are AI, antibodies, fluctuation, CAR-T cells, structural biology, and MD simulation.
*Illustrative imageNorovirus Vaccine
The lab lists a norovirus vaccine as one of its themes. In the researcher profile, vaccines are registered as a research keyword.
*Illustrative imagePreparation and Optimization of Immunotoxins
This research prepares and optimizes immunotoxins. In the researcher profile, immunotoxins are registered as a research keyword.
*Illustrative imageX-ray Crystallography of Proteins
The lab works on X-ray crystallography of proteins. In the researcher profile, it is registered as a long-term theme with a research period running until 2034.
MembersFaculty
- ProfessorJose Caaveiro
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Smallpox vaccine” Photo Credit: James Gathany Content Providers(s): CDC / Public domain (cropped)
- Using AI in Antibody Research: “Antibody IgG1 surface” Tokenzero / CC BY-SA 4.0 (cropped)
- Norovirus Vaccine: “Norovirus” Charles D. Humphrey, USCDCP / CC0 (cropped)
- Preparation and Optimization of Immunotoxins: “DKKSP1 scorpion toxin protein structure” designed by software SWISS-MODEL from expasy.com / CC BY-SA 4.0 (cropped)
- X-ray Crystallography of Proteins: “CSIRO ScienceImage 418 XRay Crystallography Protein Crystals” division, CSIRO / CC BY 3.0 (cropped)
- Related lab (タンパク質工学
（カアベイロ ホセ） ): “SHOC2 protein crystal structure” Achaparro0600 / CC BY-SA 4.0 (cropped) - Related lab (〈鉱物学〉): “Brown calcite crystals ( )” James Petts from London, England / CC BY-SA 2.0 (cropped)
- Related lab (鉱物学
（桑原 義博） ): “Gypsum - Sieroszowice mine, Lubin, Lower Silesia, Poland” Ivar Leidus / CC BY-SA 4.0 (cropped) - Related lab (〈筋細胞生物学〉): “Chick embryo 3d” PaulT (Gunther Tschuch) / CC BY-SA 4.0 (cropped)
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