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Medical Biophysical Chemistry Lab
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The lab explores materials that manipulate cells, from the perspectives of mechanics and physics.
AboutAbout the lab
Exploring cell-manipulating materials through mechanics and physics
The Medical Biophysical Chemistry Lab (Kidoaki Lab) studies the engineering of materials that manipulate cells, and the biophysics of cells, in order to broaden the foundations of regenerative medical engineering.
It aims to create biomaterials that control how cells and tissues respond to their mechanical environment (mechanobiology).
Within the lab there is also the Ise Group, which uses glycopolymers to control cell functions.
Key terms
- Mechanobiology
- A field that examines how the functions of cells and tissues relate to their mechanical environment
- Glycopolymer
- A synthetic polymer with sugar chains as side chains. The lab works with those carrying N-acetylglucosamine
- Vimentin
- A protein known as a cytoskeletal molecule. It appears in large amounts at lesion sites in cancerous and fibrotic tissue
ResearchResearch themes
To broaden the foundations of regenerative medical engineering, the lab conducts research from two sides: materials engineering for cell manipulation and cell biophysics. Its research overview lists cell-manipulating mechanobiomaterials, cell-manipulating interface and gel technology, cell-manipulating fiber technology, control of stem cell aging, and glycopolymer drug delivery systems (DDS) as its major projects.
*Illustrative imageCell-manipulating mechanobiomaterials
The lab works on creating materials that manipulate stem cells, materials that manipulate cell movement, materials that induce tissue regeneration, and materials used for diagnosing cancer cells.
*Illustrative imageMatrix engineering
Using electrospinning, the lab develops extracellular matrices, scaffolds, and devices for tissue engineering.
*Illustrative imageAssembly of biopolymers and molecular biomechanics
From a physical chemistry standpoint, the lab studies the processes by which DNA and proteins separate and come together, as well as self-assembly and molecular biomechanics.
*Illustrative imageControlling cell functions with glycopolymers
Making use of the interaction between glycopolymers carrying N-acetylglucosamine and vimentin on the cell surface, the lab aims to build therapeutic strategies, such as diagnostics and drug delivery systems for various diseases.
MembersFaculty
The lab's members are faculty, technical staff, and master's and undergraduate students.As of 2026
- ProfessorSatoru Kidoaki
- Associate ProfessorHirohiko Ise
- Assistant ProfessorTassaneeya Kuboki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Jiyong Lee, CELL CUBE WITH PURPLE MANIPULATION, 2012” Jiyongleeglas / CC BY 4.0 (cropped)
- Cell-manipulating mechanobiomaterials: “Class 3 Road Base” RAMCO / CC BY-SA 4.0 (cropped)
- Matrix engineering: “Extracellular Matrix-es” Twooars De la traducción Lorito / CC BY-SA 4.0 (cropped)
- Assembly of biopolymers and molecular biomechanics: “Détails du Conformateur 01” Sophie Jeannin / CC BY-SA 4.0 (cropped)
- Controlling cell functions with glycopolymers: “B cell function” Arizona Science Center / CC BY-SA 3.0 (cropped)
- Related lab (Energy Device Chemistry Lab): “Sodium chloride solution” Hawesthoughts / CC0 (cropped)
- Related lab (Energy Device Chemistry Lab): “Redox bat 2” Kavin Teenakul / CC BY-SA 4.0 (cropped)
- Related lab (Multidimensional Molecular Arrangement Lab): “Numbered organic molecule” Wyatt Tyrone Smith / CC BY-SA 4.0 (cropped)
- Related lab (Complex Molecular Systems Lab): “FiveMinEpoxy” Taktoa / CC BY-SA 3.0 (cropped)
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