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Jinbo-Kotani Lab
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The lab uncovers how the brain, heart, and nerve cells work, using measurement and mathematics.
AboutAbout the lab
Exploring the mechanisms of life, from cells to whole organisms.
The Kotani-Shimba Lab studies life phenomena, from the cellular level to the whole organism.
The body works through a hierarchy, from molecules and cells to organs and the whole organism.
Using nanotechnology and measurement methods that combine multiple approaches, the lab collects information at each level of this hierarchy, integrates the data, and carries out mathematical analysis and modeling.
The lab's work spans a wide range, from basic understanding of life phenomena to developing technologies that support daily life.
Key terms
- Mathematical model
- A representation of how a phenomenon works, expressed in mathematical equations. Computer calculations can be used to reproduce or predict experimental results.
- Nonlinear dynamics
- A field of mathematics and physics that studies the behavior of complex, changing systems in which cause and effect are not simply proportional.
- Autonomic nervous system
- The nerves that regulate bodily functions such as heartbeat, blood pressure, and breathing, independently of one's own will.
NewsLab news
A master's student received the Excellent Poster Award at the IEEJ Electronics, Information and Systems Society Conference
A master's student received the Department Chair's Award of the Department of Human and Engineered Environmental Studies
A master's student received the Excellent Presentation Award at an IEEJ technical meeting
Students received the Graduation Thesis Award of the Department of Precision Engineering and the SICE Excellent Student Award
Students received the Excellent Poster Award and other awards at the IEEJ Electronics, Information and Systems Society Conference
ResearchResearch themes
The lab studies life phenomena, from cells to whole organisms. By measuring information at various levels of biological systems and carrying out mathematical analysis and modeling from the perspective of data integration, it aims to understand the essence of life phenomena.
*Illustrative imageSolving the mechanisms of life phenomena with mathematics
The lab analyzes processes such as brain function and gene regulation using theories from mathematics and physics, including nonlinear dynamics. Its work includes analyzing the effects of genetic mutations and proposing machine learning methods that incorporate delays in neural transmission.
*Illustrative imageReproducing brain activity with mathematical models
The lab builds mathematical models that reproduce brain activity, analyzes them with mathematical theory, and uses them to reproduce and predict experimental results.
*Illustrative imageUncovering brain information processing through measurement
The lab measures brain activity using electroencephalography (EEG), near-infrared spectroscopy (NIRS), fMRI, and magnetoencephalography (MEG). It evaluates the changes that occur during memory and calculation tasks to clarify how the brain processes information.
*Illustrative imageAutomating cardiovascular examinations and studying the autonomic nervous system
This research measures and analyzes the activity of the heart, blood vessels, and autonomic nervous system for use in diagnosis and rehabilitation. Using engineering techniques, the lab also tackles measurements and stimulation that were previously difficult.
MembersFaculty
The members of the Kotani-Shimba Lab include faculty, secretarial staff, doctoral, master's, and undergraduate students, and international research students.As of 2026
- ProfessorKiyoshi KotaniPublications ↗
- Associate ProfessorKenta ShimbaPublications ↗
- Assistant ProfessorMasato SuginoPublications ↗
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Axons Al Dente” MikeRoscopy / CC BY 4.0 (cropped)
- Solving the mechanisms of life phenomena with mathematics: “Neighborhood of attractor of discretized Lorenz system. XYZ(28) plane” German A. Chernykh & Irina A. Chernykh / CC BY-SA 4.0 (cropped)
- Reproducing brain activity with mathematical models: “Integrate-and-Fire-Neuron-Model schematic drawing” Spiking16 / CC BY-SA 4.0 (cropped)
- Uncovering brain information processing through measurement: “EEG electrode” Gspilich2 / CC BY-SA 3.0 (cropped)
- Automating cardiovascular examinations and studying the autonomic nervous system: “Heart Rate Variability HRV” Marek Jacenko thebiofeedback.com / CC BY-SA 4.0 (cropped)
- Related lab (An Lab): “Biomechanics lab with force plate” Apfriesen / CC BY-SA 4.0 (cropped)
- Related lab (Kim Lab): “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Related lab (Medical Precision Engineering Lab (Nakagawa Lab)): “HIFU Transducers Compared with Cardiac Imaging Probe” Chris Adams / CC BY-SA 4.0 (cropped)
- Related lab (Microsystem Packaging Lab): “CSIRO ScienceImage 3876 A remote sensing node part of CSIROs Fleck wireless sensor network technology” Stephan Brosnan, CSIRO / CC BY 3.0 (cropped)
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