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Bioorganic Chemistry Lab
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The lab uses organic synthesis, centered on ynolate chemistry, to create bioactive molecules.
AboutAbout the lab
Combining organic synthetic chemistry and molecular biology
The Shindo-Kano Lab (Bioorganic Chemistry) is a lab that combines organic synthetic chemistry and molecular biology in its research.
Its core is "ynolate chemistry," and on this basis the lab studies the design, synthesis, and functional control of bioactive molecules and functional molecules.
The lab also works on compounds that disrupt gravity sensing in plants, UV absorbers, and the total synthesis of natural organic compounds.
The lab belongs to the Materials Foundation Division of the Institute for Materials Chemistry and Engineering at Kyushu University, and is also a cooperating research group of the Interdisciplinary Graduate School of Engineering Sciences.
Key terms
- Ynolate
- An anion that serves as a carbon reagent in organic synthesis and is the core of the Shindo Lab's research
- Triptycene
- A functional molecule that the lab aims to synthesize using ynolates. The lab is also synthesizing linearly extended iptycenes
- Gravitropism
- The property by which plants change their direction of growth in response to the direction of gravity
NewsLab news
A paper on lipid-mimic triptycenes has been accepted by JACS
A student was selected for an Excellence Award at the 63rd Joint Kyushu Meeting of Chemistry-Related Chapters
A student received the Best Poster Award at the 36th Fukuoka Symposium
A student received the Student Excellent Presentation Award at the 146th Annual Meeting of the Pharmaceutical Society of Japan
ResearchResearch themes
The lab combines organic synthetic chemistry and molecular biology. Building on ynolate chemistry, it studies the design, synthesis, and functional control of bioactive molecules and functional molecules.
*Illustrative imageYnolate chemistry
Ynolate chemistry is the core chemistry of the Shindo Lab. The lab's website describes it as "chemistry that is the world's only one."
*Illustrative imageTriptycene chemistry
Triptycenes are functional molecules that ynolates are used to tackle. The lab is also working on the synthesis of the world's largest linear iptycene.
*Illustrative imageCompounds that disrupt gravity sensing in plants
The lab has discovered compounds that disrupt gravity sensing in plants, as gravitropism-modulating compounds (agrochemicals).
*Illustrative imageTotal synthesis of natural organic compounds
The lab has succeeded in the total synthesis of a variety of natural organic compounds.
MembersFaculty
The lab's members are faculty, doctoral and master's students, and a technical assistant.As of 2026
- ProfessorMitsuru Shindo
- Associate ProfessorArihiro Kano
- Assistant ProfessorKotaro Ochiai
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Triptycene-3D-spacefill” Jynto (talk) / CC0 (cropped)
- Ynolate chemistry: “Organic Chemistry Lab 5 by marthou” Marthou / CC BY-SA 4.0 (cropped)
- Triptycene chemistry: “Triptycene-3D-balls” Jynto (talk) / CC0 (cropped)
- Compounds that disrupt gravity sensing in plants: “Gravitropism tree” Mathieu Rodriguez / CC BY-SA 3.0 (cropped)
- Total synthesis of natural organic compounds: “Coloured column chromatography ( )” Максим Фомич / CC BY 2.0 (cropped)
- Related lab (Molecular Materials Chemistry Lab): “Scandium-triflate-hydrate-xtal-293K-Sc-coordination-3D-balls” Ben Mills / Public domain (cropped)
- Related lab (Functional Molecular Chemistry Lab): “C-H functionalization activation version 2” Alsosaid1987 / CC0 (cropped)
- Related lab (Reaction and Property Theory Lab): “Comparison of classical vs murburn enzyme mechanism” Annvinod / CC BY-SA 4.0 (cropped)
- Related lab (Nano-Interface Physical Properties Lab): “Nanočástice Au biosenzory. Změna optických vlastností nanočástic zlata v závislosti na velikosti částice” ZuzanaBrabcova / CC BY-SA 4.0 (cropped)
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