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Nano-Interface Physical Properties Lab
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The lab explores biosensing using nanoparticle self-assembly and the light of plasmons.

AboutAbout the lab
Arranging nanoparticles to confine light.
The Nano-Interface Physical Properties Lab studies how molecules and nanoparticles can be self-assembled into materials with new functions, and applies them to biosensing.
In particular, it investigates broadly plasmon resonance, an optical phenomenon that occurs at the interfaces between metals and organic materials.
A recent topic is the “plasmonic nanosheet,” which makes use of the property that silver nanoparticles spontaneously form two-dimensional crystals at the air-water interface.
On the lab’s website, it is presented under the name “Tamada-Okamoto Lab.”
Key terms
- Plasmon resonance
- A phenomenon in which metal nanoparticles with a diameter of 100 nm or less resonate with light and strongly confine light of a specific wavelength nearby
- Self-assembly
- The process in which particles and the like gather spontaneously to form an ordered arrangement. In this lab, silver nanoparticles form a two-dimensional crystal at the air-water interface
- TIRF microscope
- A microscope that uses light under total internal reflection conditions to observe fluorescence near the interface of a substrate with a high signal-to-noise ratio
ResearchResearch themes
Under the keyword nanobiotechnology, the lab investigates plasmon resonance, an optical phenomenon that occurs at interfaces between metals and organic materials, with the aim of applying it to areas such as biosensing. A recent topic is the “plasmonic nanosheet,” made by arranging silver nanoparticles.
*Illustrative imagePlasmonic nanosheets of silver nanoparticles
The lab synthesizes large quantities of silver nanoparticles of uniform size and spreads them at the air-water interface to form two-dimensional self-assembled films. It calls these films “plasmonic nanosheets” and studies their optical and electrical properties.
*Illustrative imageA biosensor readable by the naked eye
Using a stacked sheet of silver nanoparticles as the detection substrate, the lab succeeded in adsorbing a trace amount of gold nanoparticles through an antigen-antibody reaction and detecting it visually. The lab says this method makes it possible to carry out health-related diagnostics and environmental tests easily in ordinary households.
*Illustrative imageHigh-sensitivity fluorescence imaging of nano-interfaces
Using a plasmonic nanosheet as the observation substrate for a TIRF microscope, the lab enhanced emission from the interface and succeeded in fluorescence observation of a narrower nano-interface region of 20 nm or less. It observes the adhesion interface of adherent cells at high resolution.
*Illustrative imagePlasmonics and electronics
The lab develops highly efficient LEDs and solar cells that use surface plasmon resonance, and conducts basic research on them. It also studies the properties of conduction electrons under plasmon resonance, based on the electrical properties of metal nanoparticle sheets.
MembersFaculty
The members of the Nano-Interface Physical Properties Lab are faculty members, master’s students, fourth-year undergraduates, and technical staff.As of 2026
- ProfessorKaoru Tamada
- Associate ProfessorYusuke Arima
- Assistant ProfessorYuto Kajino
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Nanočástice Au biosenzory. Změna optických vlastností nanočástic zlata v závislosti na velikosti částice” ZuzanaBrabcova / CC BY-SA 4.0 (cropped)
- Plasmonic nanosheets of silver nanoparticles: “Příprava nanočástic stříbra” ZuzanaBrabcova / CC BY-SA 4.0 (cropped)
- A biosensor readable by the naked eye: “Comp.Urine.Test.Strip” J3D3 / CC BY-SA 3.0 (cropped)
- High-sensitivity fluorescence imaging of nano-interfaces: “Fluorescence in calcite” Jan Pavelka / CC BY-SA 4.0 (cropped)
- Plasmonics and electronics: “Gold nanoparticles as indicators” Valeg96 / CC BY-SA 4.0 (cropped)
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