LAB LOGA page on LabLog, a review site (not the lab's official page)
Orthodontics Lab
Machine-translated · View original
An orthodontics lab that investigates the causes of malocclusion through the growth of the jaw and facial bones.
AboutAbout the lab
Analyzing the causes of malocclusion at the molecular level.
The Orthodontics Lab conducts research that analyzes, at the molecular level, abnormalities in the growth and development of the jaw and facial bones and the teeth that cause malocclusion.
The lab does not view malocclusion as merely a problem of tooth alignment. It studies malocclusion on the premise that its cause lies in the foundation: the jaw and facial bones and the temporomandibular joint.
In addition to studying tooth development and how cartilage and bone cells respond to force, the lab works on finite element analysis and the evaluation of masticatory muscle fatigue.
The lab's website is published as the website of the Orthodontic Clinic at Kyushu University Hospital, together with information on orthodontic treatment and care.
Key terms
- Malocclusion
- A condition in which the teeth are misaligned or the bite is poor. If left untreated, it can raise the risk of cavities and periodontal disease.
- MicroRNA
- Small RNAs that suppress mRNA translation and play important roles in development and cell differentiation.
- Mechanical stimulation
- Stimulation of cells by applied force, also called mechanical stress. It is one of the factors that regulate the differentiation of mesenchymal cells.
- Finite element analysis
- A computational method used in biomechanics research. The lab used it to identify the factors behind orthodontic anchor screws falling out.
NewsLab news
Recruitment of new department members for Reiwa 9 (FY2027), Orthodontics Lab (second round)
A faculty member of the Orthodontics Lab receives an award at the FDCU International Symposium
A faculty member of the Orthodontics Lab receives the MBSJ Poster Award 2025 at the 48th Annual Meeting of the Molecular Biology Society of Japan
ResearchResearch themes
The lab analyzes at the molecular level abnormalities in the growth and development of the jaw and facial bones and the teeth that cause malocclusion, aiming to get to the core of the problems malocclusion poses. It studies tooth development, craniofacial formation, and the mechanisms by which bone and cartilage cells respond to force.
*Illustrative imageAnalysis of genes involved in tooth development
The lab comprehensively analyzed genes that act in the early stages of tooth development and identified tooth-specific groups of genes. These are thought to be important for tooth morphogenesis, differentiation, and mineralization, and the lab continues its analysis using molecular biology methods.
*Illustrative imageEmbryonic craniofacial formation and microRNAs
Focusing on microRNAs, which suppress mRNA translation, the lab comprehensively examines the craniofacial region during the embryonic period. It has shown that miRNA-200a regulates cell proliferation and differentiation in the mandibular condylar cartilage of mouse embryos.
*Illustrative imageFactors that regulate mandibular formation
Embryonic patterning is regulated temporally and spatially by cytokines, growth factors, transcription factors, and other factors. The lab focuses in particular on how fibroblast growth factor (FGF) and its related factors regulate mandibular formation during mandibular organogenesis.
*Illustrative imageHow chondrocytes respond to force
Mechanical stress (mechanical stimulation) is one of the factors that regulate the differentiation of mesenchymal cells. Among the components of the skeletal system, the lab focuses on chondrocytes, aiming to elucidate the mechanisms by which mechanical stretch stimulation regulates cartilage differentiation.
MembersFaculty
- ProfessorIchiro Takahashi
- Associate ProfessorNaoto Haruyama
- LecturerToru Kitahara
- LecturerKeigo Yosizaki
- Assistant ProfessorFumie Terao
- Assistant ProfessorHidenobu Hiura
- Assistant ProfessorKaai Deguchi
- Assistant ProfessorAyaka Hirayama
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Orthodontics Lab
Oral Pathology LabFaculty of Dental Science, Department of DentistryIntegrating pathological diagnosis, education, and research …
Pediatric Oral Medicine LabFaculty of Dental Science, Department of DentistryTooth development and elucidation of the onset of hereditary…
Advanced Dental Care Evaluation and Development LabFaculty of Dental Science, Department of DentistrySafety and efficacy of state-of-the-art medical materials us…
Oral Imaging Science LabFaculty of Dental Science, Department of DentistryDiagnostic imaging in the oral region, particularly CT, ultr…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cephalometric radiograph” ANUG / CC BY-SA 4.0 (cropped)
- Analysis of genes involved in tooth development: “Dental Laboratory Technician - DPLA - 146cf b5a9205a456” Department of Labor. 1913 / Public domain (cropped)
- Embryonic craniofacial formation and microRNAs: “Figure-miARN2-v1” Drgububu / CC BY-SA 4.0 (cropped)
- Factors that regulate mandibular formation: “Jaw bone 2” Tiia Monto / CC BY-SA 4.0 (cropped)
- How chondrocytes respond to force: “Cartilage hyaline1” Echinaceapallida / CC BY-SA 4.0 (cropped)
- Related lab (Oral Pathology Lab): “1963. Fundamental research on pathogenic micro-organisms is aided by the use of the electron microscope. Corvallis, Oregon. ( )” R6, State & Private Forestry, Forest Health Protection / Public domain (cropped)
- Related lab (Pediatric Oral Medicine Lab): “Pediatric Dentistry Residents with pre-doctoral students at Give Kids a Smile 2014” Brendan John / CC BY 3.0 (cropped)
- Related lab (Advanced Dental Care Evaluation and Development Lab): “Warwick james dental elevators” Sadandy / CC BY-SA 4.0 (cropped)
- Related lab (Oral Imaging Science Lab): “Dental X-rays” Dmitry G / Public domain (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.