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Medicine and Clinical Science Lab
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A department of internal medicine that answers questions arising in clinical practice through research.

AboutAbout the lab
Creating a department of internal medicine that carries on its tradition and excels in clinical practice
The lab is the Second Department of Internal Medicine at Kyushu University, where clinical care, education, and research are carried out in an integrated way.
Since its founding in 1905, it has built a system capable of handling a wide range of diseases as a general internal medicine department.
The cerebral circulation, kidney, gastrointestinal, hypertension, diabetes, endocrinology, liver, and Hisayama Study labs work together in patient care.
In research, the lab places importance on answering questions that arise in clinical practice through research.
Key terms
- General internal medicine
- Internal medicine that handles a wide range of diseases. The system this department has built since its founding to meet the needs of each era.
- Hisayama Study
- A study that began in 1961. It forms the foundation of this department's research.
- Neurovascular unit
- A term referring to the interaction between blood vessels and neurons/glia at the microvascular level.
NewsLab news
A paper by Prof. Ago and colleagues was published in Journal of Cerebral Blood Flow & Metabolism
A paper by Prof. Ago and colleagues was published in The Journal of nutrition
A paper by Prof. Ago and colleagues was published in Cerebrovascular diseases extra
A paper by Prof. Ago and colleagues was published in Journal of renal nutrition : the official journal of the Co…
A paper by Prof. Ago and colleagues was published in Journal of the American Heart Association
ResearchResearch themes
Placing importance on answering questions that arise in clinical practice through research, the lab works to elucidate the pathophysiology of lifestyle-related diseases, stroke, kidney disease, and gastrointestinal disease. In recent years, it has been advancing collaboration with genomic medicine and AI technology, and has begun new challenges toward realizing personalized medicine.
*Illustrative imageElucidating disease mechanisms based on the Hisayama Study
Building on the Hisayama Study, which began in 1961, the lab combines clinical epidemiological research using large-scale disease cohorts with basic research to tackle the pathophysiology of lifestyle-related diseases, stroke, kidney disease, and gastrointestinal disease.
*Illustrative imageMechanisms and repair of cerebrovascular disease
With the interaction between blood vessels and neurons/glia (the neurovascular unit) in mind, the lab investigates the mechanisms by which cerebrovascular disease, dementia, epilepsy, and headache arise, as well as the mechanisms of tissue repair and functional recovery after brain injury. It also studies how reactive oxygen species are involved in the onset of cardiovascular disease.
*Illustrative imageThe Fukuoka Stroke Registry study
Together with the major institutions in Fukuoka Prefecture that treat acute cerebrovascular disease, the lab conducts a stroke database study, the Fukuoka Stroke Registry (FSR). In addition to epidemiological research, it collects genomes and plasma to search for genes and biomarkers related to cerebrovascular disease, and also focuses on identifying clinical factors that may determine functional outcome.
MembersFaculty
The members of the Medicine and Clinical Science Lab consist of faculty, graduate students, and staff physicians.As of 2026
- ProfessorTetsuro Ago
- Associate ProfessorToshiaki Nakano
- Associate Professor (Comprehensive Renal Failure Therapeutics)Kumiko Torisu
- Clinical Associate ProfessorAtsushi Umeno
- Project Assistant Professor (Comprehensive Renal Failure Therapeutics)Akihiro Tsuchimoto
- Concurrent LecturerKeisuke Kawasaki
- Assistant Professor (Emergency and Critical Care Center)Yuji Ikuno
- LecturerShinji Nakamura
- Associate Professor (Kidney Disease Treatment Department)Shunsuke Yamada
- Concurrent LecturerToshiaki Okuma
- Assistant ProfessorShoji Tsuneyoshi
- Concurrent LecturerTakuya Kiyohara
- Concurrent LecturerYuta Matsukuma
- Concurrent LecturerYuichi Matsuno
- Assistant ProfessorMinako Inoue
- Assistant ProfessorTomohiro Nagasue
- Assistant ProfessorKenji Ueki
- Assistant ProfessorYutaro Ihara
- Assistant Professor (Emergency and Critical Care Center)Satomi Maizuki
- Assistant ProfessorMasamitsu Takashima
- Assistant ProfessorAisuke Imazu
- Assistant ProfessorDaiki Higashi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Stethoscope-2” this version: Sonarpulse. origenal:Huji / Public domain (cropped)
- Elucidating disease mechanisms based on the Hisayama Study: “NABL Accredited Pathology Lab and Diagnostic Centre in Kharghar, Navi Mumbai - Full Body Checkup, CBC, Thyroid Blood Test and Home Blood Collection” Goleisureintl / CC BY 4.0 (cropped)
- Mechanisms and repair of cerebrovascular disease: “Cerebral angiography, arteria vertebralis sinister injection” Lipothymia / Public domain (cropped)
- The Fukuoka Stroke Registry study: “Brain CT Scan for Stroke Diagnosis” Goleisureintl / CC BY 4.0 (cropped)
- Related lab (Hygiene and Public Health Lab): “Elderly Woman Walking Outside” Thomas Taylor Hammond ( ) / CC BY-SA 4.0 (cropped)
- Related lab (Medicine and Bioregulatory Science Lab): “Insulin struct” User:AtikaAtikawa / CC BY-SA 4.0 (cropped)
- Related lab (Cardiovascular Medicine Lab): “Echocardiogram 4chambers” 作者不詳 / Public domain (cropped)
- Related lab (Respiratory Medicine Lab): “X-ray of lobar pneumonia” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Written informed consent was obtained from the individual, including online publication. / CC0 (cropped)
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